ACE PROXYVON (200/20mg)
Aceclofenac 200 mg, Rabeprazole 20 mg
Wockhardt Health Care Ltd.
It comes as a tablet to take by mouth, with food.
Store it in an airtight container in a cool dry place. Protect from light
In patients with severe ulcer Gastrointestinal bleeding Hypersensitivity
Anthrax : Anthrax is a life-threatening infectious disease that normally affects animals, especially ruminants (such as goats, cattle, sheep, and horses). Anthrax can be transmitted to humans by contact with infected animals or their products. In recent years, anthrax has received a great deal of attention as it has become clear that the infection can also be spread by a bioterrorist attack or by biological warfare. Anthrax does not spread from person to person. What causes anthrax? The agent of anthrax is a bacterium called Bacillus anthracis. While other investigators discovered the anthrax bacillus, it was a German physician and scientist, Dr. Robert Koch, who proved that the anthrax bacterium was the cause of a disease that affected farm animals in his community. Under the microscope, the bacteria look like large rods. However, in the soil, where they live, anthrax organisms exist in a dormant form called spores. These spores are very hardy and difficult to destroy. Inhalation or gastro-intestinal anthrax should be treated initially with either ciprofloxacin or doxycycline combined with one or two other antibacterials (such as amoxicillin, benzylpenicillin, chloramphenicol, clarithromycin, clindamycin, imipenem with cilastatin, rifampicin [unlicensed indication], and vancomycin). When the condition improves and the sensitivity of the Bacillus anthracis strain is known, treatment may be switched to a single antibacterial. Treatment should continue for 60 days because germination may be delayed. Cutaneous anthrax should be treated with either ciprofloxacin [unlicensed indication] or doxycycline [unlicensed indication] for 7 days. Treatment may be switched to amoxicillin if the infecting strain is susceptible. Treatment may need to be extended to 60 days if exposure is due to aerosol. A combination of antibacterials for 14 days is recommended for cutaneous anthrax with systemic features, extensive oedema, or lesions of the head or neck.
Increased risk of renal impairment when Aceclofenac given with ACE inhibitors (perindopril ,captopril, enalapril, lisinopril and ramipril ), Angiotensin - II receptor antagonists ( Losartan, candesartan , telmisartan and Valsartan ), Ciclosporin,Tacrolimus and Diuretics. Antagonise hypotensive effect with ACE inhibitors, Adrenergic neurone blockers,Alphablockers, Angiotensin -II receptor antagonists, Betablockers, Calcium channel blockers, clonidine, Diazoxide, Hydralazine, Methyl dopa, Minoxidine, Moxonidine, Nitrates and Nitroprusside. Increased risk of bleeding with Antidepressants, Clopidrogel, Erlotinib, Iloprost, Pentoxifylline Sibutramine and Venlafaxine. Aceclofenac probably reduce excretion of lithium (increased risk of toxicity). Possible increased risk of convulsions when Aceclofenac given with quinolones.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.