ALDACTIDE
Spironolactone 25 mg, hydroflumethiazide 25 mg
R.P.G. Life Science Limited
It available as a tablet to take by mouth, with food.
Store it at room temperature (25°C)
Anuria and hypersensitivity
Hypertension : Hypertension, also referred to as high blood pressure, is a condition in which the arteries have persistently elevated blood pressure. Every time the human heart beats, it pumps blood to the whole body through the arteries. Blood pressure is the force of blood pushing up against the blood vessel walls. The higher the pressure the harder the heart has to pump. Hypertension can lead to damaged organs, as well as several illnesses, such as renal failure (kidney failure), aneurysm, heart failure, stroke, or heart attack. The normal level for blood pressure is below 120/80, where 120 represents the systolic measurement (peak pressure in the arteries) and 80 represents the diastolic measurement (minimum pressure in the arteries). Blood pressure between 120/80 and 139/89 is called pre hypertension (to denote increased risk of hypertension), and a blood pressure of 140/90 or above is considered hypertension. Hypertension may be classified as essential or secondary. Essential hypertension is the term for high blood pressure with unknown cause. It accounts for about 95% of cases. Secondary hypertension is the term for high blood pressure with a known direct cause, such as kidney disease, tumors, or birth control pills.
Angiotensin-converting enzyme inhibitors: Increased hypotension if aggressively diuresed with a thiazide diuretic. Beta-blockers increase hyperglycemic effects in Type 2 diabetes mellitus. Cyclosporine and thiazides can increase the risk of gout or renal toxicity; avoid concurrent use. Digoxin toxicity can be exacerbated if a thiazide induces hypokalemia or hypomagnesemia. Lithium toxicity can occur by reducing renal excretion of lithium; monitor lithium concentration and adjust as needed. Neuromuscular blocking agents can prolong blockade; monitor serum potassium and neuromuscular status. NSAIDs can decrease the efficacy of thiazides reducing the diuretic and antihypertensive effects.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.