AROFEN 150MG INJECTION 3ML
Diclofenac 150 mg
Makers Laboratories
Diclofenac is available as a tablet, and liquid-filled capsule, a hard gelatin capsule, an extended-release (long-acting) tablet, a delayed-release (releases medication in the intestine) tablet, and as packets of powder for solution (to be mixed with water) and taken orally. Take tabllets or capsules with meals, milk, or antacids to minimize GI distress. Diclofenac liquid-filled capsules are usually taken 4 times a day and diclofenac hard gelatin capsules are usually taken three times a day on an empty stomach.
Store it at room temperature and away from excess heat and moisture.
Active peptic ulcer Hypersensitivity to diclofenac or other NSAIDs Treatment of perioperative pain in CABG surgery 3rd trimester of pregnancy Topical: Not to be applied onto damaged or non-intact skin
Anxiety Disorder : DEFINITION Anxiety can be described as an uncomfortable feeling of vague fear or apprehension accompanied by characteristic physical sensations. It is a normal and often beneficial response to situations that humans perceive as threatening, frightful, or otherwise disturbing. PATHOPHYSIOLOGY A neurocircuit arising from the output pathways of the central nucleus of the amygdala is thought to mediate fear and anxiety responses in humans.Dysregulated or exaggerated output through various amygdala-related circuits may be a common element underlying the different anxiety disorders, but the specific type of dysfunction probably differs among the various disorders. Several neurotransmitter systems have been linked to the neurobiology of anxiety: the inhibitory amino acid, ?-aminobutyric acid (GABA); the monoamine neurotransmitters, serotonin and norepinephrine; the excitatory amino acid, glutamate; and the neuropeptides, cholecystokinin (CCK), corticotrophin-releasing factor (CRF), neuropeptide Y (NPY), and substance P.2,3 Much of the evidence for these biologic processes has come from research on drugs that are used either to treat anxiety or to induce anxiety. Discovery of the anxiolytic effects of benzodiazepines in the early 1960s marked the beginning of this era of research. However, the anxiety-reducing properties of alcohol and barbiturates were recognized long before that time. Panic attack : Panic attacks are periods of intense fear or apprehension that are of sudden onset and of variable duration from minutes to hours.Panic attacks usually begin abruptly, may reach a peak within 10 to 20 minutes, but may continue for hours in some cases.Panic attacks usually subside on their own over the next several hours.Drug therapy include Benzodiazepines (alprazolam, clonazepam and lorazepam), Beta Blockers( carvedilol, propranolol, and timolol), Selective Serotonin Reuptake Inhibitors (fluoxetine, paroxetine and sertraline) and Selective and Norepinephrine Reuptake Inhibitors (Venlafaxine ).
Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants. Potentially fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.