AXIDOL 50MG TABLET DT
Tramadol 50mg
AXON
It available as a tablet, capsule taken orally with or without food. It is available as a solution for injection to be administered by a healthcare provider into the vein or large muscle.
Store it at room temperature (25°C).
Patients with suicidal tendency Raised intracranial pressure Severe renal impairment Acute alcoholism Lactation
Peptic ulcer disease : A peptic ulcer is a defect in the lining of the stomach or the first part of the small intestine, an area called the duodenum.A peptic ulcer in the stomach is called a gastric ulcer. An ulcer in the duodenum is called a duodenal ulcer. Major causes of Peptic ulcer disease(PUD) are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs), especially in patients with risk factors such as smoking and alcohol use. Diagnostic testing for PUD includes procedures used to document the presence of an ulcer, usually endoscopy, and tests that document the presence of H. pylori infection. Eradication of H. pylori, involving the use of at least two antibiotics and a proton-pump inhibitor (PPI) for 10 to 14 days, plays a major role in curing PUD. Antibiotics to treat PUD include clarithromycin , amoxicillin, tetracycline, or metronidazole. Proton pump inhibitors (omeprazole, lansoprazole or esomeprazole), bismuth subsalicylate and ulcer protectants( sucralfate) are the other mainstays in PUD treatment. Gastritis : Gastritis is inflammation of the lining of the stomach and has many possible causes.Common causes of gastritis are excessive alcoholconsumption or prolonged use of nonsteroidal anti-inflammatory drugs (also known as NSAIDs) such as aspirin or ibuprofen. Antacids neutralize stomach acid and can provide fast pain relief. When antacids do not provide enough relief, medications such as cimetidine, ranitidine, nizatidine or famotidine that help reduce the amount of acid the stomach produces are often prescribed.[ An even more effective way to limit stomach acid production is using Proton pump inhibitors.This class of medications includes omeprazole, lansoprazole, rabeprazole, and esomeprazole.
Alcohol (Ethanol) Moderate Drug Interaction Reduced analgesic efficacy of tramadol with carbamezapine,5-HT3 receptor antagonist eg:Ondansetron Possible increase in anticoagulation with warfarin Antidepressants SSRI: increased risk of CNS toxicity when tramadol given with SSRIs. Antidepressants Tricyclic: increased risk of CNS toxicity when tramadol given with tricyclics Coumarins: tramadol enhances anticoagulant effect of coumarins Seligiline: caution with tramadol advised by manufacturer of selegiline.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.