BIOTRAM 50MG INJECTION 2ML
Tramadol 50 mg
Biochem Pharmaceuticals
It available as a tablet, capsule taken orally with or without food. It is available as a solution for injection to be administered by a healthcare provider into the vein or large muscle.
Store it at room temperature (25°C).
Patients with suicidal tendency Raised intracranial pressure Severe renal impairment Acute alcoholism Lactation
Malaria : Malaria is a mosquito-borne disease caused by a parasite. People with malaria often experience fever, chills, and flu-like illness. Left untreated, they may develop severe complications and die. In 2010 an estimated 219 million cases of malaria occurred worldwide and 660,000 people died, most (91%) in the African Region Quinine derivatives /Quinine sulphate: Destroys the asexual forms of Plasmodium in three days. Used in the treatment of cerebral malaria, it clears the clogs in the brain capillaries caused by Plasmodium falciparum. Not toxic in recommended dosage but excessive dosage may cause temporary deafness. Pregnant women should not be given quinine derivatives. Acridine derivatives/Mepacrine and Quinacrine: Destroys the asexual forms of plasmodium after the third or fourth day. Toxic effects are temporary yellow coloration of skin, face, eyes and urine. Biguanie/Paludrine: Destroys the tissue forms and can be used as a prophylactic drug. - Prophylactic dosage – 300 mgs once a week - For treatment – 300 mgs daily for 5 to 10 days
Alcohol (Ethanol) Moderate Drug Interaction Reduced analgesic efficacy of tramadol with carbamezapine,5-HT3 receptor antagonist eg:Ondansetron Possible increase in anticoagulation with warfarin Antidepressants SSRI: increased risk of CNS toxicity when tramadol given with SSRIs. Antidepressants Tricyclic: increased risk of CNS toxicity when tramadol given with tricyclics Coumarins: tramadol enhances anticoagulant effect of coumarins Seligiline: caution with tramadol advised by manufacturer of selegiline.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.