Cobagen
Methylcobalamin 500 mcg, gabapentin 300 mg.
Macleods Pharmaceuticals Limited
It is available as a tablet, capsule, and syrup taken orally, with or without food.
Store at 25°C.
Hypersensitivity.
Gout : Gout is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The initial aim of treatment is to settle the symptoms of an acute attack. Repeated attacks can be prevented by different drugs used to reduce the serum uric acid levels. Ice applied for 20 to 30 minutes several times a day decreases pain. Options for acute treatment include nonsteroidal anti-inflammatory drugs (NSAIDs), colchicineand steroids,while options for prevention include allopurinol, febuxostat and probenecid. Lowering uric acid levels can cure the disease.Treatment of comorbidities is also important.
Analgesics: bioavailability of gabapentin increased by morphine. Antacids: absorption of gabapentin reduced by antacids. Antidepressants: anticonvulsant effect of antiepileptics possibly antagonised by MAOIs and .tricyclicrelated antidepressants (convulsive threshold lowered); anticonvulsant effect of antiepileptics antagonised by .SSRIs and .tricyclics (convulsive threshold lowered); avoid concomitant use of antiepileptics with .St John’s wort. Antimalarials: possible increased risk of convulsions when antiepileptics given with chloroquine and hydroxychloroquine; anticonvulsant effect of antiepileptics antagonised by .mefloquine. Orlistat: possible increased risk of convulsions when anti epileptics given with orlistat.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.