Dopagyt
METHYLDOPA
Themis Medicare Limited
It available as a tablet and liquid to take by mouth, with or without food.
Store it in a well-closed container at controlled room temperature (15-30°C).
Depression Active liver disease Hypersensitivity Therapy with MAO inhibitors Pheochromocytoma Porphyria
Spasticity : Spasticity is stiff or rigid muscles. It may also be called unusual tightness or increased muscle tone. Reflexes (for example, a knee-jerk reflex) are stronger or exaggerated. The condition can interfere with walking, movement, or speech. Symptoms Episodes of spasticity can range from very mild to debilitating and painful. Signs of spasticity include: • muscle tightness • joint stiffness • involuntary jerky movements • exaggeration of reflexes • unusual posture • abnormal positioning of fingers, wrists, arms, or shoulders • muscle spasms • involuntary crossing of the legs (this is called "scissoring" because the legs cross like the tip of a pair of scissors) • difficulty controlling the muscles used to speak • muscle contraction that limits your range of motion or prevents your joints from extending all the way • pain in the affected muscles and joints • back pain • difficulty moving Spasticity can be triggered when you change position or move suddenly. Other spasm triggers include high humidity, extreme heat, extreme cold, infection, and clothing that is too tight. Causes of Spasticity The main cause of spasticity is damage to the nerve pathways that control the movement of muscles. This can be a symptom of a variety of conditions and diseases, including: • brain injury • spinal cord injury • stroke • cerebral palsy • multiple sclerosis (MS) • amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease) • hereditary spastic paraplegias • adrenoleukodystrophy • phenylketonuria • Krabbe disease Medication • Medical interventions may include such medications as baclofen, diazepam, dantrolene, or clonazepam. Phenol injections can be used, or botulinum toxin injections into the muscle belly, to attempt to dampen the signals between nerve and muscle.
ACE inhibitors : enhanced hypotensive effect when methyldopa given with ACE inhibitors Adrenergic neurone blockers : enhanced hypotensive effect when methyldopa given with adrenergic neurone blockers. Alcohol :enhanced hypotensive effect when methyldopa given with alcohol Aldesleukin: enhanced hypotensive effect when methyldopa given with aldesleukin Alpha-blockers :enhanced hypotensive effect when methyldopa given with alpha-blockers
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.