ECOSMIN
isosorbide 5-mononitrate, aspirin .
Usv Limited.
It should be taken on an empty stomach (i.e. At least one hour before food or two hours after food).
Store at a temperature not exceeding 30°C.
Severe hypotension or anaemia Hypovolaemia Heart failure due to obstruction or raised intracranial pressure due to head trauma or cerebral haemorrhage.
Spasticity : Spasticity is stiff or rigid muscles. It may also be called unusual tightness or increased muscle tone. Reflexes (for example, a knee-jerk reflex) are stronger or exaggerated. The condition can interfere with walking, movement, or speech. Symptoms Episodes of spasticity can range from very mild to debilitating and painful. Signs of spasticity include: • muscle tightness • joint stiffness • involuntary jerky movements • exaggeration of reflexes • unusual posture • abnormal positioning of fingers, wrists, arms, or shoulders • muscle spasms • involuntary crossing of the legs (this is called "scissoring" because the legs cross like the tip of a pair of scissors) • difficulty controlling the muscles used to speak • muscle contraction that limits your range of motion or prevents your joints from extending all the way • pain in the affected muscles and joints • back pain • difficulty moving Spasticity can be triggered when you change position or move suddenly. Other spasm triggers include high humidity, extreme heat, extreme cold, infection, and clothing that is too tight. Causes of Spasticity The main cause of spasticity is damage to the nerve pathways that control the movement of muscles. This can be a symptom of a variety of conditions and diseases, including: • brain injury • spinal cord injury • stroke • cerebral palsy • multiple sclerosis (MS) • amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease) • hereditary spastic paraplegias • adrenoleukodystrophy • phenylketonuria • Krabbe disease Medication • Medical interventions may include such medications as baclofen, diazepam, dantrolene, or clonazepam. Phenol injections can be used, or botulinum toxin injections into the muscle belly, to attempt to dampen the signals between nerve and muscle.
Sildenafil : Concomitant administration of isosorbide mononitrate and sildenafil an potentiate the vasodilatory effect of isosorbide mononitrate with the potential result of serious side-effects such as syncope or myocardial infarction. Sulfhydryl-containing compounds : The metabolism of organic nitrates to nitric oxide is dependent on the presence of sulfhydryl groups in the muscle. The combination of oral N-acetylcysteine and a single dose of sustained-release isosorbide mononitrate 60 mg significantly prolonged the total exercise time in patients with angina pectoris and angiographically proven significant coronary artery disease, when compared with isosorbide mononitrate alone. Propranolol : The addition of isosorbide mononitrate to propranolol treatment in patients with cirrhosis and portal hypertension caused a marked fall in portal pressure, a reduction in hepatic blood flow, cardiac output and mean arterial blood pressure, but no additional change in azygos blood flow. Phe
Whether you're looking for a doctor for dealing with your own medical condition, click here to find right physician.
It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.