GATIFAR 400MG TABLET
Gatifloxacin 400 mg
Unichem Laboratories Ltd
It may be taken with or without food.
NA
Hypersensitivity Children <18 yr; concurrent use of class IA or III antiarrhythmics QT-prolongation drug Diabetics Pregnancy Lactation.
Spasticity : Spasticity is stiff or rigid muscles. It may also be called unusual tightness or increased muscle tone. Reflexes (for example, a knee-jerk reflex) are stronger or exaggerated. The condition can interfere with walking, movement, or speech. Symptoms Episodes of spasticity can range from very mild to debilitating and painful. Signs of spasticity include: • muscle tightness • joint stiffness • involuntary jerky movements • exaggeration of reflexes • unusual posture • abnormal positioning of fingers, wrists, arms, or shoulders • muscle spasms • involuntary crossing of the legs (this is called "scissoring" because the legs cross like the tip of a pair of scissors) • difficulty controlling the muscles used to speak • muscle contraction that limits your range of motion or prevents your joints from extending all the way • pain in the affected muscles and joints • back pain • difficulty moving Spasticity can be triggered when you change position or move suddenly. Other spasm triggers include high humidity, extreme heat, extreme cold, infection, and clothing that is too tight. Causes of Spasticity The main cause of spasticity is damage to the nerve pathways that control the movement of muscles. This can be a symptom of a variety of conditions and diseases, including: • brain injury • spinal cord injury • stroke • cerebral palsy • multiple sclerosis (MS) • amyotrophic lateral sclerosis (ALS, Lou Gehrig’s disease) • hereditary spastic paraplegias • adrenoleukodystrophy • phenylketonuria • Krabbe disease Medication • Medical interventions may include such medications as baclofen, diazepam, dantrolene, or clonazepam. Phenol injections can be used, or botulinum toxin injections into the muscle belly, to attempt to dampen the signals between nerve and muscle.
Antacids, ferrous salts, bismuth subsalicylate, sucralfate and zinc salts reduce bioavailability of gatifloxacin. May increase digoxin plasma levels. Probenecid, cimetidine and loop diuretics increase gatifloxacin levels. NSAIDs may increase the risk of CNS stimulation and convulsions. Concurrent use of bepridil, cisapride, erythromycin, pentamidine, phenothiazines, or TCAs may prolong QT interval. Concurrent corticosteroid therapy may increase the risk of tendon rupture. Increased risk of hypoglycaemia when used with oral antidiabetic agents. May enhance hypoprothrombinaemic effects of oral anticoagulants.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.