GATIPAN 400MG TABLET
Gatifloxacin 400 mg
Panjon Pharma
It may be taken with or without food.
NA
Hypersensitivity Children <18 yr; concurrent use of class IA or III antiarrhythmics QT-prolongation drug Diabetics Pregnancy Lactation.
Spasticity : Spasticity is a feature of altered skeletal muscle performance in muscle tone involving hypertonia; it is also referred to as an unusual "tightness", stiffness, or "pull" of muscles. The cause of spasticity is not really known, but there are several theories. In general, spasticity develops when an imbalance occurs in the excitatory and inhibitory input to a motor neurons caused by damage to the spinal cord and/or central nervous system. The damage causes a change in the balance of signals between the nervous system and the muscles, leading to increased excitability in the muscles. Spasticity is found in conditions where the brain and/or spinal cord are damaged or fail to develop normally; these include cerebral palsy, multiple sclerosis, spinal cord injury and acquired brain injury including stroke. Damage to the CNS as a result of stroke or spinal cord injury, alter of peripheral nerves in the affected region. Spasticity : Spasticity is a feature of altered skeletal muscle performance in muscle tone involving hypertonia; it is also referred to as an unusual "tightness", stiffness, or "pull" of muscles. The cause of spasticity is not really known, but there are several theories. In general, spasticity develops when an imbalance occurs in the excitatory and inhibitory input to a motor neurons caused by damage to the spinal cord and/or central nervous system. The damage causes a change in the balance of signals between the nervous system and the muscles, leading to increased excitability in the muscles. Spasticity is found in conditions where the brain and/or spinal cord are damaged or fail to develop normally; these include cerebral palsy, multiple sclerosis, spinal cord injury and acquired brain injury including stroke. Damage to the CNS as a result of stroke or spinal cord injury, alter of peripheral nerves in the affected region.
Antacids, ferrous salts, bismuth subsalicylate, sucralfate and zinc salts reduce bioavailability of gatifloxacin. May increase digoxin plasma levels. Probenecid, cimetidine and loop diuretics increase gatifloxacin levels. NSAIDs may increase the risk of CNS stimulation and convulsions. Concurrent use of bepridil, cisapride, erythromycin, pentamidine, phenothiazines, or TCAs may prolong QT interval. Concurrent corticosteroid therapy may increase the risk of tendon rupture. Increased risk of hypoglycaemia when used with oral antidiabetic agents. May enhance hypoprothrombinaemic effects of oral anticoagulants.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.