Arthritis : Arthritis is a form of joint disorder that involves inflammation of one or more joints. There are over 100 different forms of arthritis. The most common form, osteoarthritis (degenerative joint disease), is a result of trauma to the joint, infection of the joint, or age. Other arthritis forms are rheumatoid arthritis, psoriatic arthritis, and related autoimmune diseases. Septic arthritis is caused by joint infection.
Drugs used
Aceclofenac, Abatacept, Adalimumab, Celecoxib, Cyclosporine, Diclofenac, Diflunisal, Etoricoxib, Flurbiprofen, Hydrocortisone, Hydroxychloroquine, Ibuprofen, Mefenamic Acid, Meloxicam, Sulindac and Tenoxicam
Pemphigus : Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. There are two main types: Pemphigus vulgaris and Pemphigus foliaceus. Pemphigus vulgaris is the most common form. Pemphigus can occur at any age, but often strikes people in middle age or older.If not treated, Pemphigus can be fatal from an overwhelming infection of the sores. The most common treatment is the administration of oral steroids, especially prednisone, often in high doses. The side effects of corticosteroids may require the use of so-called steroid-sparing or adjuvant drugs. Intravenous gamma globulin (IVIG) may be useful in severe cases, especially paraneoplastic pemphigus. Mild cases sometimes respond to the application of topical steroids. Rituximab was found to improve severe cases of Pemphigus vulgaris.
Psoriasis : Psoriasis a complex, chronic, multifactorial, inflammatory disease that involves hyperproliferation of the keratinocytes in the epidermis, with an increase in the epidermal cell turnover rate. Environmental, genetic, and immunologic factors appear to play a role. The disease most commonly manifests on the skin of the elbows, knees, scalp, lumbosacral areas, intergluteal clefts, and glans penis. In up to 30% of patients, the joints are also affected.
Medications used in the management of psoriasis include Topical corticosteroids (eg, triamcinolone acetonide 0.025-0.1% cream, betamethasone 0.025-0.1% cream), Ophthalmic corticosteroids (eg, prednisolone acetate 1% ophthalmic, dexamethasone ophthalmic), Intramuscular corticosteroids (eg, triamcinolone). Coal tar ,Keratolytic agents (eg, anthralin), Vitamin D analogs (eg, calcitriol ointment, calcipotriene, calcipotriene and betamethasone topical ointment) and Topical retinoids (eg, tazarotene aqueous gel and cream 0.05% and 0.1%) are frequently used in the management of Psoriasis. Other choices include Antimetabolites (eg, methotrexate), Immunomodulators (eg, tacrolimus topical 0.1%, cyclosporine, alefacept, ustekinumab), TNF inhibitors (eg, infliximab, etanercept, adalimumab) and Systemic antipsoriatic agents. (eg, ustekinumab)