ISOMEG 20MG TABLET
Isosorbide Mononitrate20 mg
Alembic Ltd
It should be taken on an empty stomach (i.e. At least one hour before food or two hours after food).
Store at a temperature not exceeding 30°C.
Severe hypotension or anaemia Hypovolaemia Heart failure due to obstruction or raised intracranial pressure due to head trauma or cerebral haemorrhage.
Amenorrhea : Is the absence of a menstrual period in a woman of reproductive age, which may temporary or permanent. Amenorrhea can be classified as primary or secondary. Primary Amenorrhea It is defined as an absence of secondary sexual characteristics by age 14 with no menarche or normal secondary sexual characteristics but no menarche by 16 years of age. And it may due to congenital absence of the uterus, failure of the ovary to receive or maintain egg cells or delay in pubertal development. Where as secondary Amenorrhea is the absence of menstrual periods for three consecutive cycles or a time period of more than six months in a woman who was previously menstruating and is often caused by hormonal disturbances from the hypothalamus and the pituitary gland, from premature menopause or intrauterine scar formation. Treatment 1. Drugs for treatment of Primary Amenorrhea are Estrogen and Progesterone 2. Drugs for treatment of Secondary Amenorrhea are Medroxyprogesterone, Progesterone and Norethindrone acetate
Sildenafil : Concomitant administration of isosorbide mononitrate and sildenafil an potentiate the vasodilatory effect of isosorbide mononitrate with the potential result of serious side-effects such as syncope or myocardial infarction. Sulfhydryl-containing compounds : The metabolism of organic nitrates to nitric oxide is dependent on the presence of sulfhydryl groups in the muscle. The combination of oral N-acetylcysteine and a single dose of sustained-release isosorbide mononitrate 60 mg significantly prolonged the total exercise time in patients with angina pectoris and angiographically proven significant coronary artery disease, when compared with isosorbide mononitrate alone. Propranolol : The addition of isosorbide mononitrate to propranolol treatment in patients with cirrhosis and portal hypertension caused a marked fall in portal pressure, a reduction in hepatic blood flow, cardiac output and mean arterial blood pressure, but no additional change in azygos blood flow. Phe
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.