IVAMAC 5MG TABLET
Ivabradine 5 mg
Macleods Pharmaceuticals Limited
It is available as a tablet taken orally, with food.
Store it at room temperature (25°C).
Severe heart disease Hypersensitivity
Anemia : Anemia is the most common disorder of the blood. Anemia is a medical condition in which a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. Anemic men hemoglobin level is less than 13.5 gram/100 and for a anemic women hemoglobin level is less than 12.0 gram/100 ml. Anemia is caused by either a decrease in production of red blood cells or hemoglobin, or an increase in loss or destruction of red blood cells. Some patients with anemia have no symptoms. Others may feel tired, easily fatigued, appear pale, a feeling of heart racing, short of breath, and/or worsening of heart problems. Anemia can be detected by a simple blood test called a complete blood cell count (CBC). The treatment of the anemia varies greatly and very much depends on the particular cause. Treatment – Treatment of anemia is done by 1. Oral iron 2. Injectable iron 3. Blood transfusions 4. Human Erythropoietin Injection Depression : Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings and sense of well-being In general the type of treatment includepsychotherapy and/or antidepressants, alternative therapies, or active intervention. The most important classes of antidepressants are the selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Other drugs used or proposed for the treatment of depression include buprenorphine,tryptophan,low-dose antipsychotics,and St John's wort.
Concomitant use with QT-prolonging drugs (e.g. quinidine, disopyramide, bepridil, sotalol, ibutilide, amiodarone, pimozide, ziprasidone, sertinole, mefloquine, halofantrine, pentamide, cisapride, erythromycin IV) is not recommended as QT prolongation may be enhanced by heart rate reduction. Concentrations may increase when used with CYP3A4 inhibitors. Use with verapamil or diltiazem (moderate CYP3A4 inhibitors) is not recommended. If used with other moderate CYP3A4 inhibitors (e.g. fluconazole), may consider starting at lower dose and with heart rate monitoring if resting heart rate >60 beats/min. Concentration may be reduced with CYP3A4 inducers (e.g. rifampicin, barbiturates, phenytoin, St John's Wort) and may require Ivabradine dose adjustment. Concurrent use with potent CYP3A4 inhibitors is contraindicated; e.g. azole antifungals (ketoconazole, itraconazole), macrolides (clarithromycin, erythromycin PO, josamycin, telithromycin), HIV protease inhibitors.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.