LEKGAT 400MG TABLET
Gatifloxacin400 mg
JB Chemicals & Pharmaceuticals Ltd
It may be taken with or without food.
NA
Hypersensitivity Children <18 yr; concurrent use of class IA or III antiarrhythmics QT-prolongation drug Diabetics Pregnancy Lactation.
Acute diarrhoea : World Health Organization defined Diarrhea as condition having three or more loose or liquid stools per day, or as having more stools than is normal for that person. Acute diarrhea is defined as an abnormally frequent discharge of semisolid or fluid fecal matter from the bowel, lasting less than 14 days, by World Gastroenterology Organisation. The priority in acute diarrhoea, is the prevention or reversal of fluid and electrolyte depletion.This is particularly important in infants and in frail and elderly patients. Drugs used in the treatment of Acute diarrhoea are (1) Oral rehydration preparations - ORAL REHYDRATION SALTS (ORS) (2) Antimotility drugs - CO-PHENOTROPE , LOPERAMIDE HYDROCHLORIDE (3) Antispasmodics - ATROPINE SULPHATE,DICYCLOVERINE HYDROCHLORIDE.HYOSCINE BUTYLBROMIDE and PROPANTHELINE BROMIDE (4) Antibacterial drugs - Ciprofloxacin, erythromycin,azithromycin,cefotaxime
Antacids, ferrous salts, bismuth subsalicylate, sucralfate and zinc salts reduce bioavailability of gatifloxacin. May increase digoxin plasma levels. Probenecid, cimetidine and loop diuretics increase gatifloxacin levels. NSAIDs may increase the risk of CNS stimulation and convulsions. Concurrent use of bepridil, cisapride, erythromycin, pentamidine, phenothiazines, or TCAs may prolong QT interval. Concurrent corticosteroid therapy may increase the risk of tendon rupture. Increased risk of hypoglycaemia when used with oral antidiabetic agents. May enhance hypoprothrombinaemic effects of oral anticoagulants.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.