Fever : Fever is one of the most common medical signs and is characterized by an elevation of body temperature above the normal range of 97.7–99.5 °F (36.5–37.5 °C) due to an increase in the temperature regulatory set-point. This increase in set-point triggers increased muscle tone and chills.
Fever is an important component of the immune response, though its role is not completely understood. Physicians believe that an elevated body temperature has several effects. The immune system chemicals that react with the fever-inducing agent and trigger the resetting of the thermostat also increase the production of cells that fight off the invading bacteria or viruses. Higher temperatures also inhibit the growth of some bacteria, while at the same time speeding up the chemical reactions that help the body's cells repair themselves. In addition, the increased heart rate that may accompany the changes in blood circulation also speeds the arrival of white blood cells to the sites of infection.
Drugs used – Acetaminophen, Mefenamic acid, Aspirin, Ibuprofen, Ketoprofen,and Naproxen
Back pain : Back pain is pain felt in the back that usually originates from the muscles, nerves, bones, joints or other structures in the spine.
Treatment
Heat therapy, Cold compression therapy (e.g. ice or cold pack application,The short term use of muscle relaxants ,Non-steroidal anti-inflammatory drugs ,Massage, posture training courses and physical exercises might help with relieving the pain. Acupuncture has some proven benefit for back painEducation, and attitude adjustment to focus on psychological or emotional causes- respondent-cognitive therapy and progressive relaxation therapy can reduce chronic pain. Only a minority of back pain patients (most estimates are 1% - 10%) require surgery.
Inflammation : "A fundamental pathologic process consisting of a dynamic complex of histologically apparent cytologic changes, cellular infiltration, and mediator release that occurs in the affected blood vessels and adjacent tissues in response to an injury or abnormal stimulation caused by a physical, chemical, or biologic agent, including the local reactions and resulting morphologic changes; the destruction or removal of the injurious material; and the responses that lead to repair and healing.
Inflammation is the body's attempt at self-protection; the aim being to remove harmful stimuli, including damaged cells, irritants, or pathogens - and begin the healing process.
When something harmful or irritating affects a part of our body, there is a biological response to try to remove it, the signs and symptoms of inflammation, specifically acute inflammation, show that the body is trying to heal itself. Inflammation does not mean infection, even when an infection causes inflammation. Infection is caused by a bacterium, virus or fungus, while inflammation is the body's response to it.
Acute inflammation - starts rapidly (rapid onset) and quickly becomes severe. Signs and symptoms are only present for a few days, but in some cases may persist for a few weeks.
Examples of diseases, conditions, and situations which can result in acute inflammation include: acute bronchitis, infected ingrown toenail, sore throat from a cold or flu, a scratch/cut on the skin, exercise (especially intense training), acute appendicitis, acute dermatitis, acute tonsillitis, acute infective meningitis, acute sinusitis, or a blow.
Chronic inflammation - this means long-term inflammation, which can last for several months and even years. It can result from:
? Failure to eliminate whatever was causing an acute inflammation
? An autoimmune response to a self antigen - the immune system attacks healthy tissue, mistaking it (them) for harmful pathogens.
? A chronic irritant of low intensity that persists
Examples of diseases and conditions with chronic inflammation include: asthma, chronicpeptic ulcer, tuberculosis, rheumatoid arthritis, chronic periodontitis, ulcerative colitis andCrohn's disease, chronic sinusitis, and chronic active hepatitis cancers, rheumatoid arthritis, atherosclerosis, periodontitis, and hay fever
Drugs Used _ NSAID’S ( Aspirin, Ibuprofen, Diclofenac Sodium, Aceclofenac , Acetaminophen) and Corticosteroids ( Both Mineralocorticoids and Glucocorticoids)
Osteoarthritis : Osteoarthritis also called Degenerative joint disease, OA, Osteoarthrosis . Osteoarthritis (OA) is the most common joint disorder, which is due to aging and wear and tear on a joint. Osteoarthritis is a normal result of aging. It is also caused by "wear and tear" on a joint.
• Cartilage is the firm, rubbery tissue that cushions your bones at the joints, and allows bones to glide over one another.
• If the cartilage breaks down and wears away, the bones rub together. This causes pain, swelling, and stiffness.
• Bony spurs or extra bone may form around the joint. The ligaments and muscles around the joint become weaker and stiffer.
Symptoms
Pain and stiffness in the joints are the most common symptoms. The pain is often worse after exercise and when you put weight or pressure on the joint.
MEDICATIONS
Over-the-counter pain relievers, which you can buy without a prescription, can help with OA symptoms. Most doctors recommend acetaminophen (Tylenol) first, because it has fewer side effects than other drugs. If your pain continues, your doctor may recommend nonsteroidal anti-inflammatory drugs (NSAIDs). Types of NSAIDs include aspirin, ibuprofen, and naproxen.
Other medications or supplements that you may use include:
• Corticosteroids injected right into the joint to reduce swelling and pain
• Over-the-counter remedies such as glucosamine and chondroitin sulfate
• Capsaicin (Zostrix) skin cream to relieve pain
• Artificial joint fluid (Synvisc, Hyalgan) can be injected into the knee to relieve pain for 3 - 6 months