NUPARIN 25000IU INJECTION
Unfractionated Heparins Systemic(25000 iu)
Troikka Pharmaceuticals Limited
It is available as a solution for injection to be administered by a healthcare provider into the vein.
Store at a temperature not exceeding 30°C.
Hypersensitivity to heparin Haemophilia and other haemorrhagic disorders Thrombocytopenia Peptic ulcer Recent cerebral haemorrhage Severe hypertension Severe liver or renal disease After major trauma or recent surgery (especially to eye or nervous system) Threatened abortion Piles Bacterial endocarditis Large malignancies Tuberculosis Lumbar puncture Chronic alcoholics Acetylsalicylic acid and other antiplatelet drugs
Migraine : Migraine is a chronic neurological disorder characterized by recurrent moderate to severe headaches often in association with a number of autonomic nervous system symptoms. Migraine is a severe, painful headache that is often preceded or accompanied by sensory warning signs such as flashes of light, blind spots, tingling in the arms and legs, nausea, vomiting, and increased sensitivity to light and sound. Medication Preventive migraine medications are considered effective if they reduce the frequency or severity of the migraine attacks by at least 50%. Guidelines are fairly consistent in rating topiramate, divalproex/sodium valproate, propranolol, and metoprolol as having the highest level of evidence for first-line use. Recommendations regarding effectiveness varied however for gabapentin. Timolol is also effective for migraine prevention and in reducing migraine attack frequency and severity, while frovatriptan is effective for prevention of menstrual migraine. Amitriptyline and venlafaxine are probably also effective. Angiotensin inhibition by either an angiotensin-converting enzyme inhibitor orangiotensin II receptor antagonist may reduce attacks. Botox has been found to be useful in those with chronic migraines but not those with episodic ones.
Cephalosporins which contain the MTT side chain may increase the risk of hemorrhage. Drugs which affect platelet function (eg, aspirin, NSAIDs, dipyridamole, ticlopidine, clopidogrel) may potentiate the risk of hemorrhage. Nitroglycerin (I.V.) may decrease heparin's anticoagulant effect. This interaction has not been validated in some studies, and may only occur at high nitroglycerin dosages. Penicillins (parenteral) may prolong bleeding time via inhibition of platelet aggregation, potentially increasing the risk of hemorrhage. Thrombolytic agents increase the risk of hemorrhage. Warfarin: Risk of bleeding may be increased during concurrent therapy. Heparin is commonly continued during the initiation of warfarin therapy to assure anticoagulation and to protect against possible transient hypercoagulability. Other drugs reported to increase heparin's anticoagulant effect include antihistamines, tetracycline, quinine, nicotine, and cardiac glycosides (digoxin).
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.