brand name : Nalox

Generic name : Naloxone

Basic Info

Use of Drug

Opioid overdosage
Postoperative respiratory
Depression

Category Of Drug

Pure opioid antagonist

Side Effects

	Occur secondarily to reversal (withdrawal) of narcotic analgesia and sedation. 

	Mental depression, apathy, inability to concentrate, sleepiness, irritability, anorexia, nausea, and vomiting in high oral doses during initial treatment of opiate addiction. 

	Severe cardiopulmonary effects (e.g. hypotension, hypertension, ventricular tachycardia and fibrillation, dyspnoea, pulmonary oedema, cardiac arrest) in postoperative patients, most frequently in those with preexisting CV disease. 

	Recurrence of respiratory depression in long-acting opioids

Drug Dose Information

Intravenous injection:

Subcutaneous or intramuscular route (if i.v. route is not feasible but the dose is same, can be given oral as well).
Adult-
Opioid poisoning: Start with 0.4 to 2 mg (at all ages) as intravenous bolus, Repeat every 2 minutes if no response to a total of
10 mg. Once response occurs start infusion of naloxone at 2/3rd the total loading dose given every hour with continous monitoring
for reccurence of respiratory depression. May require additional bolus during infusion.

Child- 
Opioid poisoning: 10 µg/kg, followed by 100 µg/kg if there is no response.

Precautions

Patients physically dependent on opioids, or who have received large doses of opioids (acute withdrawal syndrome may be precipitated). 

Pregnancy and lactation.

Brand Information

Brand Name	Nalox
Contains	NALOXONE
Manufacturer Name	Not Available

Brand Specifications
	Unit	Quantity	Price	Type
1	400 mcg	1 ml x 5	390.0000	Injection

How To Take

It is usually given as an injection by a doctor or hospital staff.

Storage

Injection: Store it at room temperature (25°C). Protect from light.

Interactions

Decreased effect of opioid analgesics. Acute withdrawal reaction in physically dependent patients may occur with opioid analgesics. Severe cardiopulmonary effects may occur with cardiotoxic drugs.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : Nalox

Generic name : Naloxone

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : Nalox

Generic name : Naloxone

Basic Info

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