OFLOKEM SUSPENSION
Ofloxacin
Alkem Laboratories
It is available as a tablet taken orally, with or without food. It also available as eye drops to instill into the affected eyes as directed by your physician.
Tablets: Store protected from light and moisture. Eye Drops: Store protected from light.
Hypersensitivity.
Asthma : According to WHO - Asthma attacks all age groups but often starts in childhood. It is a disease characterized by recurrent attacks of breathlessness and wheezing, which vary in severity and frequency from person to person. In an individual, they may occur from hour to hour and day to day. This condition is due to inflammation of the air passages in the lungs and affects the sensitivity of the nerve endings in the airways so they become easily irritated. In an attack, the lining of the passages swell causing the airways to narrow and reducing the flow of air in and out of the lungs. Classification of drugs 1. Bronchodialators A. Sympathomimetics : Adrenaline, Ephedrine, Isoprenaline, Salbutamol, Terbutaline, Bambuterol, Salmetrol, Formoterol. B. Methylxanthines : Theophylline, Aminophylline, Hydroxyethyl theophylline. C. Anticholinergics: Atropine, Ipratropium bromide 2. Leukotrienne antagonis - Montelukast, Zafirlukast 3. Mast cell stabilizers : Sodium cromglycate, Nedocromil,Krtotifen. 4. Corticosteroids : a) Systemic : Hydrocortisone, Prednisolone and others b) Inhalational : Beclomethasone dipropionate, Budesonide, Flunisolide
Probenecid decreases elimination. Antacids may reduce ofloxacin absorption, avoid for 2 hr either side of administration. Cimetidine may increase ofloxacin concentrations. Monitor blood glucose in patients on antidiabetic medication. Potentially Fatal: Corticosteroids may increase risk of tendon rupture. Increases effects of oral anticoagulants, ciclosporin, theophylline. Increased risk of seizures with NSAIDs. Avoid in patients taking QT prolonging medication (e.g. class Ia or III antiarrythmics, astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines and some TCA).
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.