brand name : Protamine Sulphate

Generic name : Protamine

Basic Info

Use of Drug

Prescribed for reversing the anticoagulant effects of heparin. 

When mixed with insulin, protamines slow down the onset and increase the duration of insulin action (see NPH insulin).

Cardiopulmonary bypass surgery to neutralize the anti-clotting effects of heparin. Adverse effects include increased pulmonary artery pressure and decrease peripheral blood pressure, myocardial oxygen consumption, cardiac output, and heart rate.

An antidote for heparin overdose.

Category Of Drug

Heparin antagonist

Side Effects

Heart - Low blood pressure, slow heart rate, and circulatory collapse.

CNS - Lassitude.

Gastrointestinal - Nausea and vomiting.

Respiratory - Shortness of breath, lung swelling and acute pulmonary hypertension.

Miscellaneous - Severe respiratory distress, poor blood circulation, noncardiogenic lung swelling; transient flushing and feeling of warmth and back pain.

Drug Dose Information

IV- 
1 mg for each 90 units of heparin derived from lung tissue or 115 units of heparin derived from intestinal mucosa.

Precautions

Pregnancy
Pediatric patients

Brand Information

Brand Name	Protamine Sulphate
Contains	Protamine Sulphate-10 mg
Manufacturer Name	Not Available

Brand Specifications
	Unit	Quantity	Price	Type
1	10 mg	1 ml	6.9100	Injection

Storage

Store protamine sulfate injection in refrigerator (36° to 46°F). Do not freeze.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : Protamine Sulphate

Generic name : Protamine

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : Protamine Sulphate

Generic name : Protamine

Basic Info

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