brand name : REGGI 10MG TABLET

Generic name : Metoclopramide

Basic Info

Use of Drug

Nausea and vomiting in gastrointestinal disorders and treatment with cytotoxics or radiotherapy

Gastro-oesophageal reflux disease

Gastroparesis

Premedication and postoperatively; aid to gastrointestinal
intubation

Nausea and vomiting in migraine

Diabetic gastric stasis

Category Of Drug

Antiemetics

Side Effects

Heart- Acute heart failure, slow heart rate, fluid retention, high blood pressure, low blood pressure and fast heart rate. 

  Central Nervous System- Sedation, dizziness, restlessness, involuntary body movements, spasms, depression, malignant neuroleptic syndrome (condition where patient experiences rigidity, decreased consciousness, fever and fluctuating blood pressure and heart rate – may be fatal). 

  Gastrointestinal- Bowel disturbances, primarily diarrhea and nausea. 

  Skin- Transient flushing of face or upper body with high IV doses. 

  Hormone- Galactorrhea ( spontaneous flow of milk from the breast), breast enlargement in men and increase in serum prolactin. 

  Genitourinary- Absence of a menstrual period, elevation of aldosterone, fluid retention, impotence, incontinence and urinary frequency. 

  Liver- Liver toxicity (rare). 

  Blood- Decrease in white blood cells and changes in hemoglobin. 

  Hypersensitivity- Rapid swelling of dermis, including glossal or laryngeal

Drug Dose Information

Oral or intramuscular injection or Slow intravenous injection
Adult- Nausea and vomiting, gastroesophageal reflux, gastroparesis: (over 1 to 2 min for slow intravenous injection), 10 mg 3 times daily. 15 to 19 years (under 60 kg) 5 mg 3 times daily. 

Aid to gastrointestinal intubation: 20 mg as a single dose 5 to 10
min before examination; Adolescent (15 to 19 years), 10 mg.
Child- Up to 1 year (up to 10 kg) 1 mg twice daily; 1 to 3years (10 to 14 kg) 1 mg 2 to 3 times daily; 3 to 5 years (15 to 19 kg) 2 mg
2 to3 times daily; 5 to 9 years (20 to 29 kg) 2.5 mg 3 times daily; 9 to 14 years (30 kg and over) 5 mg 3 times daily (usual max. 500 µg/
kg daily, particularly for children and young adult).

Slow intravenous injection only
Adult- Premedication: 10 mg as a single dose.

Precautions

Elderly
Children and young adults\
Hepatic impairment
Renal impairment
Pregnancy 
May mask underlying disorders such as cerebral irritation
Avoid for 3-4 days after gastrointestinal surgery
Lactation 
Interactions
Parkinson’s disease
Epilepsy
Depression
Porphyria
Hypertension
Cirrhosis
Congestive heart failure

Brand Information

Brand Name	REGGI 10MG TABLET
Contains	Metoclopramide 10 mg
Manufacturer Name	Menarini

Brand Specifications
	Unit	Quantity	Price	Type
1	10's	1Strip	7.0400	Tablet

It is available as a tablet, an orally disintegrating (dissolving) tablet, and a solution (liquid) taken orally. It is usually taken 4 times a day on an empty stomach, 30 minutes before each meal and at bedtime. Injection is administered by health care providers into the vein.

Storage

Store protected from light and moisture.

Contra Indications

Gastrointestinal obstruction Haemorrhage or perforation 3-4 days after gastrointestinal surgery Convulsive disorders Pheochromocytoma Hypersensitivity

Diseases

GERD : Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus The treatments for GERD include lifestyle modifications, medications, and possibly surgery. Initial treatment is frequently with a proton-pump inhibitor such as omeprazole.

Interactions

Increased sedative effects with CNS depressants. GI effects antagonised by antimuscarinics and opioids. Reduces absorption of digoxin. Increases absorption of ciclosporin, levodopa, aspirin, paracetamol. Interferes with hypoprolactinaemic effect of bromocriptine. Inhibits serum cholinesterase and prolongs neuromuscular blockade produced by suxamethonium and mivacurium. Potentially Fatal: Serotonin syndrome with sertraline (SSRI).

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brand name : REGGI 10MG TABLET

Generic name : Metoclopramide

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : REGGI 10MG TABLET

Generic name : Metoclopramide

Basic Info

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