brand name : REXTRO 200MG TABLET

Generic name : Voriconazole

Basic Info

Use of Drug

Voriconazole is an azole antifungal used to treat a variety of fungal infections.

Category Of Drug

Antifungal

Side Effects

Most Common - Visual disturbances, fever, nausea, rash, vomiting, chills, headache, abnormal liver function, fast heart rate and hallucinations. 

Body as a Whole - Abdominal pain, flu-like syndrome and weakness. 

Heart - Chest pain, vein inflammation, low blood pressure and facial swelling. 

Gastrointestinal - Nausea, vomiting, diarrhea, loss of appetite, difficulty in swallowing, indigestion, dry mouth, reflex and flatulence. 

Liver - Jaundice and liver inflammation. 

Blood - Blood dyscrasias, bruising and swelling in the extremities. 

Central Nervous System - Dizziness, hallucinations, confusion, depression, anxiety, tremor, agitation and tingling. 

Respiratory - Respiratory distress syndrome, sinus inflammation, nose bleed and difficulty in breathing. 

Skin - Rash, itching, sensitivity to light, hair loss and skin inflammation. 

Genitourinary - Kidney failure, blood in urine, impotence, urinary incontinence, urinary retention, urinary tract infection and vaginal bleeding.

Drug Dose Information

Usual Adult Dose for Aspergillosis -- Invasive:
Loading dose: 6 mg/kg IV every 12 hours for 2 doses

Maintenance dose:
IV:
Invasive aspergillosis and serious fungal infections due to Fusarium species and Scedosporium apiospermum: 4 mg/kg IV every 12 hours

Treatment must be started with the IV loading dose on Day 1 followed by the maintenance dose. IV therapy should continue for at least 7 days. Once the patient has clinically improved and can tolerate medication given by mouth, the oral tablet form or oral suspension form of voriconazole may be utilized.

Candidemia in nonneutropenic patients and other deep tissue Candida infections: 3 to 4 mg/kg IV every 12 hours

During clinical trials, patients with candidemia received 3 mg/kg IV every 12 hours as primary therapy, while patients with other deep tissue Candida infections received 4 mg/kg as salvage therapy. Appropriate dose should be based on the nature and severity of the infection.

Oral:
Less than 40 kg: 100 mg oral

Precautions

History of heart problems
Abnormal electrocardiogram (ECG)
Low level of blood minerals
Liver, kidney, pancreas, or blood disease
Who have taken chemotherapy treatment
Any allergy
Who are taking other medications
Pregnancy 
Breastfeeding

Brand Information

Brand Name	REXTRO 200MG TABLET
Contains	Voriconazole200 mg
Manufacturer Name	Dr. Reddys Laboratories Limited

Brand Specifications
	Unit	Quantity	Price	Type
1	4's	1 strip	4107.6800	Tablet

How To Take

It is available as a tablet taken orally 1 hour before food.

Storage

Store it at controlled room temperature (15° - 30°C)

Voriconazole may interact with omeprazole, clopidogrel, cyclosporine, phenytoin, OCPs, tacrolimus, anti-HIV/AIDS drugs, prednisolone, warfarin, alfentanil, methadone, NSAIDs, tranquilizers, anti-hypertensive drugs, statins, vincristine, vinblastine, calcium-channel blockers and oral anti-diabetic drugs.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : REXTRO 200MG TABLET

Generic name : Voriconazole

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : REXTRO 200MG TABLET

Generic name : Voriconazole

Basic Info

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