RIMODAR 25MG/500MG TABLET
Pyrimethamine25 mg+Sulphadoxine500 mg
Anglo - french
It is available as a tablet taken orally, after food.
Store protected from light and moisture.
Hypersensitivity to sulfonamides or pyrimethamine Severe hepatic or renal impairment (except where no alternative treatment available) Blood dyscrasias Neonates Megaloblastic anaemia and folate deficiency
Osteoporosis : Osteoporosis causes bones to become weak and brittle — so brittle that a fall or even mild stresses like bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine. Bone is living tissue, which is constantly being absorbed and replaced. Osteoporosis occurs when the creation of new bone doesn't keep up with the removal of old bone. Symptoms Signs and symptoms include: • Back pain, caused by a fractured or collapsed vertebra • Loss of height over time • A stooped posture • A bone fracture that occurs much more easily than expected Treatments For both men and women, the most widely prescribed osteoporosis medications are bisphosphonates. Examples include: • Alendronate (Fosamax, Binosto) • Risedronate (Actonel, Atelvia) • Ibandronate (Boniva) • Zoledronic acid (Reclast, Zometa)
Antifolic drugs (eg, sulfonamides, trimethoprim-sulfamethoxazole):should not be taken by patients receiving sulfadoxine/pyrimethamine Chloroquine: Incidence and severity of adverse reactions may be increased compared with taking sulfadoxine/pyrimethamine alone. Methenamine: May increase the potential for formation of insoluble precipitates in the urine Methotrexate: Methotrexate levels may increase,adjust dose as needed Tretinoin: May augment phototoxicity
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.