Regubeat
DISOPYRAMIDE
Glaxo Smithkline Pharmaceuticals Lt
It available as a capsule taken orally, with or without food.
Store it at room temperature, and in an airtight container. Keep away from children.
Patients with complete heart block Glaucoma Predisposition to urinary retention Myasthenia gravis Sinus node disease in absence of pacemaker Cardiomyopathy Cardiogenic shock Hypotension Hypersensitivity
Arrhythmia : DEFINITION Arrhythmia is defined as loss of cardiac rhythm, especially irregularity of heart-beat and is an abnormal cardiac rhythm, usually involving the change in rate or regularity and is monitored by using Electrocardiograph (ECG). PATHOPHYSIOLOGY The blood pushed from ventricles in a controlled sequence of muscle contraction. In cardiac arrhythmia, there will be disturbed in the sequence and in electrical conductivity. Arrhythmias are classified in to differentkinds depending upon the disorders of impulse generation and includes, Premature contraction - Common arrhythmia, which affect large number of people. Caffeine and stress increases the occurrence of premature beats. Tachycardia - An abnormally fast heart beats (more than 100beats/min) ,this can also lead to insufficient blood circulation. Bradycardia- An abnormally fast heart beats (more than 100beats/min). This can also lead to insufficient blood circulation. Atrial fibrillation- A rapid, irregular heart rhythm caused by abnormal electrical impulses that begins in the upper chambers of the heart.In atrial fibrillation the heart rate is even higher i.e. 500 beats/min. Atrial flutter - In atrial flutter the heart rate is 250-350 beats/min, associated with tachycardia.Commonly seen in hyperthyroidism and heart failure. Ventricular fibrillation - Life threatening condition in which the heartquivers very rapidly about 350times/min or more.This leads to rapidly fatal if not reversed by defibrillation.
Avoid other Class I antiarrhythmics and other cardiac depressants including ß-blockers except in life-threatening arrhythmias. Reduced efficacy when co-admin with phenytoin. Risk of worsening of arrhythmias, precipitation of new arrhythmias and ventricular fibrillation when used with other anti-arrhythmics.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.