Rhythmonorm
PROPAFENONE
Zydus Cadila Healthcare Ltd. (German Remedies)
It available as a tablet to take by mouth (orally), with food.
Store it in an airtight container; keep away from children and pets.
Uncontrolled heart failure Marked hypotension Severe bradycardia and heart block Conduction abnormalities Cardiogenic shock Myasthenia gravis
Arrhythmia : DEFINITION Arrhythmia is defined as loss of cardiac rhythm, especially irregularity of heart-beat and is an abnormal cardiac rhythm, usually involving the change in rate or regularity and is monitored by using Electrocardiograph (ECG). PATHOPHYSIOLOGY The blood pushed from ventricles in a controlled sequence of muscle contraction. In cardiac arrhythmia, there will be disturbed in the sequence and in electrical conductivity. Arrhythmias are classified in to differentkinds depending upon the disorders of impulse generation and includes, Premature contraction - Common arrhythmia, which affect large number of people. Caffeine and stress increases the occurrence of premature beats. Tachycardia - An abnormally fast heart beats (more than 100beats/min) ,this can also lead to insufficient blood circulation. Bradycardia- An abnormally fast heart beats (more than 100beats/min). This can also lead to insufficient blood circulation. Atrial fibrillation- A rapid, irregular heart rhythm caused by abnormal electrical impulses that begins in the upper chambers of the heart.In atrial fibrillation the heart rate is even higher i.e. 500 beats/min. Atrial flutter - In atrial flutter the heart rate is 250-350 beats/min, associated with tachycardia.Commonly seen in hyperthyroidism and heart failure. Ventricular fibrillation - Life threatening condition in which the heartquivers very rapidly about 350times/min or more.This leads to rapidly fatal if not reversed by defibrillation.
Reduced plasma levels when used with enzyme inducers e.g. rifampicin. Increased plasma levels when used with enzyme inhibitors e.g. cimetidine, fluoxetine, quinidine and HIV protease inhibitors. Absorption is reduced by orlistat. Increased risk of arrhythmias when used with antiarrhythmics/arrhythmogenic drugs. Increased serum levels of theophylline, metoprolol and propanolol when used concurrently. Increased risk of bradycardia and heart block when used with ß-blockers.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.