brand name : Rubuphine

Generic name : Nalbuphine

Basic Info

Use of Drug

Prescribed as a supplement to balanced anesthesia

For preoperative and postoperative analgesia

For obstetrical analgesia during labour and delivery

Category Of Drug

Opioid Analgesics

Side Effects

Most common - Increased sweating, nausea, vomiting, dizziness, fainting, dry mouth, and headache. 

Central Nervous System - Nervousness, depression, restlessness, crying, elevated mood, floating, hostility, unusual dreams, confusion, faintness, hallucinations, anxiety, feeling of heaviness, numbness, tingling. . 

 Heart - High blood pressure, low blood pressure and slow or fast heart rate. 

 Gastrointestinal - Cramps, indigestion and bitter taste. 

 Respiratory - Respiratory depression, difficulty in breathing and asthma. 

 Skin - Itching, burning and hives. 

 Miscellaneous - Speech difficulty, urinary urgency, blurred vision, flushing and warmth.

Drug Dose Information

Adult: IV Adjunct in balanced anesth Induction: 0.3-1 mg/kg, up to 3 mg/kg. Maintenance: 250-500 mcg/kg every 30 mins. Pain associated w/ MI 10-30 mg via slow inj, then 20-mg 30 min later if needed. IV/IM/SC Moderate to severe pain 10-20 mg 3-6 hourly as needed. Nonopioid-tolerant patients: Max: 20 mg/dose and 160 mg/day. Anesth premed 100-200 mcg/kg.

Precautions

History of breathing problems
High blood pressure
Underactive thyroid
Liver or kidney problems
Heart attack
Alcoholism
Depression
Mental illness
Suicidal thoughts
Head injury
Brain growths
Increased pressure in the head
Seizures
Any allergy
Who are taking other medications
Pregnancy 
Breastfeeding

Brand Information

Brand Name	Rubuphine
Contains	NALBUPHINE
Manufacturer Name	Not Available

Brand Specifications
	Unit	Quantity	Price	Type
1	10 mg	10 mg/ 1 amp	32.0000	Injection
2	20 mg	20 mg /1 amp	62.0000	Injection

How To Take

It is available as a solution for injection to be administered by healthcare provider into the vein, muscle or under the skin.

Interactions

Additive CNS depressant effects may occur with other CNS depressants e.g. alcohol, anaesthetics, anxiolytics, hypnotics, TCAs and antipsychotics.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : Rubuphine

Generic name : Nalbuphine

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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drug’s Side effects

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brand name : Rubuphine

Generic name : Nalbuphine

Basic Info

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drug’s Side effects

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