brand name : S OMEPREN 20MG TABLET

Generic name : Omeprazole

Basic Info

Use of Drug

Gastroesophageal reflux disease (GERD)
Helicobacter pylori infection
Duodenal ulcer
Gastric ulcers associated with continuous NSAID therapy
Zollinger-Ellison syndrome

Category Of Drug

Proton pump inhibitors

Side Effects

CNS- Headache, dizziness, drowsiness, aggression, agitation, depression, hallucination. 

 Itching, hair loss, severe allergic reactions, photosensitivity, blistering. 

Eye and ENT- Blurred vision. 

Gastrointestinal- Flatulence, abdominal pain, stomach upset, nausea, diarrhea, dry mouth, constipation, GI fungal infection, inflammation of pancreas and intestine, mouth ulcer, taste disturbance. 

Genitourinary - Breast enlargement in men, kidney disorder. 

Liver- Occurrence of confusion, altered level of consciousness and coma as a result of liver failure(Hepatic encephalopathy) , liver failure, inflammation of liver with or without jaundice. 

Blood- Decrease in white blood cells. 

Local- Injection-site reactions including mild local redness and itching with IV administration. 

Musculoskeletal- Muscular weakness, muscle pain. 

Respiratory- Asthma, respiratory tract infection.

Drug Dose Information

Oral
Orosive Oesophagitis
Adult: 40 mg once daily for 4 week, extended for another 4 week if necessary. Maintenance: 20 mg once daily.

Child: <20 kg: 10 mg once daily for 8 wk; =20 kg: 10-20 mg once daily for 8 week. 

Hepatic impairment: Severe impairment (Child-Pugh class C): Not more than 20 mg daily.

Oral :
Peptic ulcer
Adult: 20 mg bid for 7 days or 40 mg once daily for 10 days given as a triple therapy with amoxicillin and clarithromycin.

Oral:
NSAID-Associated ulcer
Adult: 20 mg once daily for 4-8 week.

Oral:
Zollinger-Ellison syndrome
Adult: Initially, 40 mg twice daily. Usual range: 80-160 mg daily. Doses >80 mg should be given in 2 divided doses.

Precautions

Pregnancy
Concomitant gastric malignancy

Brand Information

Brand Name	S OMEPREN 20MG TABLET
Contains	Esomeprazole20 mg
Manufacturer Name	Blue Cross Laboratory. ltd

Brand Specifications
	Unit	Quantity	Price	Type
1	5 mg/10 mg	10	102.1500	Tablet
2	10 mg/10 mg	10	147.6000	Tablet

How To Take

It available as a tablet or capsule to taken orally, once a day, one hour before meal.

Injection: Powder for injection: Store at (20 - 25°C). Protect from light. Reconstituted solution for injection should be stored at room temperature up to 30°C and administered within 12 hr after preparation.

Contra Indications

Hypersensitivity. It should not be co-administered with Methotrexate, clopidogrel and atazanavir.

Diseases

Asthma : According to WHO - Asthma attacks all age groups but often starts in childhood. It is a disease characterized by recurrent attacks of breathlessness and wheezing, which vary in severity and frequency from person to person. In an individual, they may occur from hour to hour and day to day. This condition is due to inflammation of the air passages in the lungs and affects the sensitivity of the nerve endings in the airways so they become easily irritated. In an attack, the lining of the passages swell causing the airways to narrow and reducing the flow of air in and out of the lungs. Classification of drugs 1. Bronchodialators A. Sympathomimetics : Adrenaline, Ephedrine, Isoprenaline, Salbutamol, Terbutaline, Bambuterol, Salmetrol, Formoterol. B. Methylxanthines : Theophylline, Aminophylline, Hydroxyethyl theophylline. C. Anticholinergics: Atropine, Ipratropium bromide 2. Leukotrienne antagonis - Montelukast, Zafirlukast 3. Mast cell stabilizers : Sodium cromglycate, Nedocromil,Krtotifen. 4. Corticosteroids : a) Systemic : Hydrocortisone, Prednisolone and others b) Inhalational : Beclomethasone dipropionate, Budesonide, Flunisolide

Interactions

May interfere with the elimination of drugs metabolised by CYP2C19. Changes in gastric pH can affect the bioavailability of ketoconazole and Fe salts. Clarithromycin and amoxicillin may increase plasma level. May cause changes to prothrombin time when used with warfarin. Avoid concurrent use with clopidogrel.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : S OMEPREN 20MG TABLET

Generic name : Omeprazole

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : S OMEPREN 20MG TABLET

Generic name : Omeprazole

Basic Info

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