brand name : S OMEPREN 40MG TABLET

Generic name : Omeprazole

Basic Info

Use of Drug

Gastroesophageal reflux disease (GERD)
Helicobacter pylori infection
Duodenal ulcer
Gastric ulcers associated with continuous NSAID therapy
Zollinger-Ellison syndrome

Category Of Drug

Proton pump inhibitors

Side Effects

CNS- Headache, dizziness, drowsiness, aggression, agitation, depression, hallucination. 

 Itching, hair loss, severe allergic reactions, photosensitivity, blistering. 

Eye and ENT- Blurred vision. 

Gastrointestinal- Flatulence, abdominal pain, stomach upset, nausea, diarrhea, dry mouth, constipation, GI fungal infection, inflammation of pancreas and intestine, mouth ulcer, taste disturbance. 

Genitourinary - Breast enlargement in men, kidney disorder. 

Liver- Occurrence of confusion, altered level of consciousness and coma as a result of liver failure(Hepatic encephalopathy) , liver failure, inflammation of liver with or without jaundice. 

Blood- Decrease in white blood cells. 

Local- Injection-site reactions including mild local redness and itching with IV administration. 

Musculoskeletal- Muscular weakness, muscle pain. 

Respiratory- Asthma, respiratory tract infection.

Drug Dose Information

Oral
Orosive Oesophagitis
Adult: 40 mg once daily for 4 week, extended for another 4 week if necessary. Maintenance: 20 mg once daily.

Child: <20 kg: 10 mg once daily for 8 wk; =20 kg: 10-20 mg once daily for 8 week. 

Hepatic impairment: Severe impairment (Child-Pugh class C): Not more than 20 mg daily.

Oral :
Peptic ulcer
Adult: 20 mg bid for 7 days or 40 mg once daily for 10 days given as a triple therapy with amoxicillin and clarithromycin.

Oral:
NSAID-Associated ulcer
Adult: 20 mg once daily for 4-8 week.

Oral:
Zollinger-Ellison syndrome
Adult: Initially, 40 mg twice daily. Usual range: 80-160 mg daily. Doses >80 mg should be given in 2 divided doses.

Precautions

Pregnancy
Concomitant gastric malignancy

Brand Information

Brand Name	S OMEPREN 40MG TABLET
Contains	Esomeprazole40 mg
Manufacturer Name	Blue Cross Laboratory. ltd

Brand Specifications
	Unit	Quantity	Price	Type
1	5 %w/v	1	58.0000	Eye drops

How To Take

It available as a tablet or capsule to taken orally, once a day, one hour before meal.

Injection: Powder for injection: Store at (20 - 25°C). Protect from light. Reconstituted solution for injection should be stored at room temperature up to 30°C and administered within 12 hr after preparation.

Contra Indications

Hypersensitivity. It should not be co-administered with Methotrexate, clopidogrel and atazanavir.

Diseases

No Disease Found

Interactions

May interfere with the elimination of drugs metabolised by CYP2C19. Changes in gastric pH can affect the bioavailability of ketoconazole and Fe salts. Clarithromycin and amoxicillin may increase plasma level. May cause changes to prothrombin time when used with warfarin. Avoid concurrent use with clopidogrel.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : S OMEPREN 40MG TABLET

Generic name : Omeprazole

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : S OMEPREN 40MG TABLET

Generic name : Omeprazole

Basic Info

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