SAFEGUARD TABLET
Diclofenac 50 mg,Misoprostol 200 mcg
Pulse Pharmaceuticals Pvt.Ltd
Diclofenac is available as a tablet, and liquid-filled capsule, a hard gelatin capsule, an extended-release (long-acting) tablet, a delayed-release (releases medication in the intestine) tablet, and as packets of powder for solution (to be mixed with water) and taken orally. Take tabllets or capsules with meals, milk, or antacids to minimize GI distress. Diclofenac liquid-filled capsules are usually taken 4 times a day and diclofenac hard gelatin capsules are usually taken three times a day on an empty stomach.
Store it at room temperature and away from excess heat and moisture.
Active peptic ulcer Hypersensitivity to diclofenac or other NSAIDs Treatment of perioperative pain in CABG surgery 3rd trimester of pregnancy Topical: Not to be applied onto damaged or non-intact skin
Osteoarthritis : Osteoarthritis also called Degenerative joint disease, OA, Osteoarthrosis . Osteoarthritis (OA) is the most common joint disorder, which is due to aging and wear and tear on a joint. Osteoarthritis is a normal result of aging. It is also caused by "wear and tear" on a joint. • Cartilage is the firm, rubbery tissue that cushions your bones at the joints, and allows bones to glide over one another. • If the cartilage breaks down and wears away, the bones rub together. This causes pain, swelling, and stiffness. • Bony spurs or extra bone may form around the joint. The ligaments and muscles around the joint become weaker and stiffer. Symptoms Pain and stiffness in the joints are the most common symptoms. The pain is often worse after exercise and when you put weight or pressure on the joint. MEDICATIONS Over-the-counter pain relievers, which you can buy without a prescription, can help with OA symptoms. Most doctors recommend acetaminophen (Tylenol) first, because it has fewer side effects than other drugs. If your pain continues, your doctor may recommend nonsteroidal anti-inflammatory drugs (NSAIDs). Types of NSAIDs include aspirin, ibuprofen, and naproxen. Other medications or supplements that you may use include: • Corticosteroids injected right into the joint to reduce swelling and pain • Over-the-counter remedies such as glucosamine and chondroitin sulfate • Capsaicin (Zostrix) skin cream to relieve pain • Artificial joint fluid (Synvisc, Hyalgan) can be injected into the knee to relieve pain for 3 - 6 months
Not to be given IV to patients who are receiving other NSAIDs or anticoagulants including low dose heparin. Renal function may be worsened when used with ciclosporin or triamterene. Altered absorption when given with sucralfate, colestyramine or colestipol. Ophthalmic application of diclofenac may reduce the efficacy of ophthalmic acetylcholine and carbachol. Increased risk of GI ulceration and bleeding when used with corticosteroids, aspirin or anticoagulants. Potentially fatal: Increases blood levels of digoxin, lithium and methotrexate. Potentiate potassium-sparing diuretics.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.