Breastcancer : Breastcancer is cancer that forms in the cells of the breasts.
Treatment
Surgery, radiation ,medications
medications
There are currently three main groups of medications used for adjuvant breast cancer treatment: hormone-blocking agents, chemotherapy, and monoclonal antibodies.
Hormone blocking therapy
tamoxifen (Nolvadex), anastrozoleor letrozole
Chemotherapy
Cyclophosphamide with doxorubicin (Adriamycin). Sometimes a taxane drug, such as docetaxel (Taxotere), is added, and the regime is then known as "CAT". Another common treatment, which produces equivalent results is cyclophosphamide, methotrexate, and fluorouracil (or "CMF").
Monoclonal antibodies - Trastuzumab
Prostate cancer : Prostate cancer is a form of cancer that develops in the prostate, a gland in the male reproductive system. Most prostate cancers are slow growing however; there are cases of aggressive prostate cancers. The cancer cells may metastasize (spread) from the prostate to other parts of the body, particularly the bones and lymph nodes. Prostate cancer may cause pain, difficulty in urinating, problems during sexual intercourse, erectile dysfunction, or death. Other symptoms can potentially develop during later stages of the disease. Abiraterone Acetate, Denosumab, Docetaxel, Leuprolide Acetate, Prednisone are some of the chemotherapeutic agents to treat prostate cancer.
Endometriosis : Endometriosis is the abnormal growth of cells (endometrial cells) similar to those that form the inside or lining the tissue of the uterus, but in a location outside of the uterus. Endometrial cells are cells that are shed each month during menstruation. The cells of endometriosis attach themselves to tissue outside the uterus and are called endometriosis implants. These implants are most commonly found on the ovaries, the Fallopian tubes, outer surfaces of the uterus or intestines, and on the surface lining of the pelvic cavity. They can also be found in the vagina, cervix, and bladder, although less commonly than other locations in the pelvis. Rarely, endometriosis implants can occur outside the pelvis, on the liver, in old surgery scars, and even in or around the lung or brain. Endometrial implants, while they can cause problems, are benign (not cancerous).
TREATMENT AND MEDICATION
Nonsteroidal anti-inflammatory drugs or NSAIDs (such as ibuprofen or naproxensodium) are commonly prescribed to help relieve pelvic pain and menstrual cramping. NSAIDs are commonly used, such as naproxen or ibuprofen, are commonly used.
Gonadotropin-releasing hormone analogs (GnRH analogs)
Gonadotropin-releasing hormone analogs (GnRH analogs) have been effectively used to relieve pain and reduce the size of endometriosis implants.
Oral contraceptive pills
Oral contraceptive pills (estrogen and progesterone in combination) are also sometimes used to treat endometriosis. The most common combination used is in the form of the oral contraceptive pill (OCP).
Progestins
Progestins [for example, medroxyprogesterone acetate, norethindrone acetate, norgestrel acetate ] are more potent than birth control pills and are recommended for women who do not obtain pain relief from or cannot take a birth control pill.
Other drugs used to treat endometriosis
Danazol
Danazol is a synthetic drug that creates a high androgen (male type hormone) and low estrogen hormonal environment by interfering with ovulation and ovarian production of estrogen.,
Aromatase inhibitors
A newer approach to the treatment of endometriosis has involved the administration of drugs known as aromatase inhibitors (for example,anastrozole and letrozole ).
Leukemia : Leukemia is cancer of the blood or bone marrow (which produces blood cells). A person who has leukemia suffers from an abnormal production of blood cells, generally leukocytes (white blood cells). The word Leukemia comes from the Greek leukos which means "white" and aima which means "blood".
The DNA of immature blood cells, mainly white cells, becomes damaged in some way. This abnormality causes the blood cells to grow and divide chaotically. Normal blood cells die after a while and are replaced by new cells which are produced in the bone marrow. The abnormal blood cells do not die so easily, and accumulate, occupying more and more space. As more and more space is occupied by these faulty blood cells there is less and less space for the normal cells - and the sufferer becomes ill. Quite simply, the bad cells crowd out the good cells in the blood.
Causes
Experts say that different leukemias have different causes. The following are either known causes, or strongly suspected causes:
? Artificial ionizing radiation
? Viruses - HTLV-1 (human T-lymphotropic virus) and HIV (human immunodeficiency virus)
? Benzene and some petrochemicals
? Alkylating chemotherapy agents used in previous cancers
? Maternal fetal transmission (rare)
? Hair dyes
? Genetic predisposition - some studies researching family history and looking at twins have indicated that some people have a higher risk of developing leukemia because of a single gene or multiple genes.
? Down syndrome - people with Down syndrome have a significantly higher risk of developing leukemia, compared to people who do not have Down syndrome. Experts say that because of this, people with certain chromosomal abnormalities may have a higher risk.
? Electromagnetic energy - studies indicate there is not enough evidence to show that ELF magnetic (not electric) fields that exist currently might cause leukemia. The IARC (International Agency for Research on Cancer) says that studies which indicate there is a risk tend to be biased and unreliable.
Signs and symptoms
Common leukemia Signs and symptoms include:
• Fever or chills
• Persistent fatigue, weakness
• Frequent or severe infections
• Losing weight without trying
• Swollen lymph nodes, enlarged liver or spleen
• Easy bleeding or bruising
• Recurrent nosebleeds
• Tiny red spots in your skin (petechiae)
• Excessive sweating, especially at night
• Bone pain or tenderness
Classification
The first type of classification is by how fast the leukemia progresses:
• Acute leukemia. In acute leukemia, the abnormal blood cells are immature blood cells (blasts). They can't carry out their normal work, and they multiply rapidly, so the disease worsens quickly. Acute leukemia requires aggressive, timely treatment.
• Chronic leukemia. This type of leukemia involves more mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years.
The second type of classification is by type of white blood cell affected:
• Lymphocytic leukemia. This type of leukemia affects the lymphoid cells (lymphocytes), which form lymphoid or lymphatic tissue. Lymphatic tissue makes up your immune system.
• Myelogenous (my-uh-LOHJ-uh-nus) leukemia. This type of leukemia affects the myeloid cells. Myeloid cells give rise to red blood cells, white blood cells and platelet-producing cells.
Types of leukemia
The major types of leukemia are:
• Acute lymphocytic leukemia (ALL). This is the most common type of leukemia in young children. ALL can also occur in adults.
• Acute myelogenous leukemia (AML). AML is a common type of leukemia. It occurs in children and adults. AML is the most common type of acute leukemia in adults.
• Chronic lymphocytic leukemia (CLL). With CLL, the most common chronic adult leukemia, you may feel well for years without needing treatment.
• Chronic myelogenous leukemia (CML). This type of leukemia mainly affects adults. A person with CML may have few or no symptoms for months or years before entering a phase in which the leukemia cells grow more quickly.
Medications
Chemotherapy for leukemia is usually a combination of drugs. This is because different drugs attack leukemia cells in different ways. The combination also helps keep the leukemia cells from becoming resistant to any one drug.
Medicine choices
For acute leukemia
Your treatment plan will include the kind of medicine that works best for the specific type or subtype of leukemia that you have.
• Acute lymphoblastic leukemia (ALL) may be treated with chemotherapy medicines (asparaginase, clofarabine, daunorubicin, doxorubicin, methotrexate,nelarabine, or vincristine) and corticosteroids (dexamethasone or prednisone).
• Acute myelogenous leukemia (AML) may be treated with chemotherapy medicines (cytarabine, daunorubicin, idarubicin, or mitoxantrone).