brand name : TOFLOX 400MG TABLET

Generic name : Ofloxacin

Basic Info

Use of Drug

Acute uncomplicated cystitis

Community acquired pneumonia

Acute exacerbation of chronic bronchitis

Category Of Drug

Fluoroquinolones

Side Effects

Most Common - Nausea, headache, sleeplessness, genital itching in women, dizziness, vaginal inflammation, diarrhea and vomiting. 

   Body as a whole - Weakness, chills, uneasiness, extremity pain and nosebleed. 

   Heart - Heart arrest, fluid retention, high blood pressure, low blood pressure, palpitations and dilatation of blood vessels. 

   Gastrointestinal - Indigestion. 

   Genitourinary - Burning, irritation, pain and rash of the female genitalia, painful menstrual period, irregular periods, painful urination, urinary frequency and urinary retention. 

   Musculoskeletal - Joint/muscle pain. 

   Central Nervous System - Seizures, anxiety, cognitive change, depression, dream abnormality, emotion, hallucinations, tingling, fainting, unsteadiness, tremor and confusion. 

   Metabolic - Increased thirst and weight loss. 

   Respiratory - Respiratory arrest, cough and runny nose. 

   Skin - Shock, increased sweating and hives. 

   Eye and ENT - Hearing loss, ringing in the ear,

Drug Dose Information

Oral
Community acquired pneumonia:
Adult- 400 mg twice daily for 10 days.

Pelvic inflammatory disease:
Adult- 400 mg twice daily for 14 days.

Complicated UTI:
Adult- 200 mg twice daily for 10 days.

Parenteral
Complicated UTI:
Adult- 200 mg daily by i.v infusion over atleast 30 minutes, max. 400 mg twice infused over at least 1 h.

Septicaemia, lower respiratory tract infection:
Adult- 200 mg twice daily by i.v infusion over at least 30 minutes, max. 400 mg twice daily infused over at least 1 h.

Bacterial corneal ulcer:
Adult- 0.3%, 1-2 drops every 30 minutes.

Ophthalmic
Bacterial conjunctivitis:
Adult- 0.3%, 1-2 drops every 2-4 h.
Child- >1year, 1-2drops every 2-4 h.

Precautions

History of joint problems
Rheumatoid arthritis
Heart, kidney, or lung transplant
Alzheimer disease
Seizures
Stroke
Central nervous system disorder
Heart, liver, or kidney disease
Decrease in blood minerals
Any allergy
Who are taking other medications
Children
Elderly
Pregnancy 
Breastfeeding

Brand Information

Brand Name	TOFLOX 400MG TABLET
Contains	Ofloxacin 400 mg
Manufacturer Name	Lincoln Pharmaceuticals Ltd

Brand Specifications
	Unit	Quantity	Price	Type
1	10ml	1Vial	2500.0000	Injection

How To Take

It is available as a tablet taken orally, with or without food. It also available as eye drops to instill into the affected eyes as directed by your physician.

Storage

Tablets: Store protected from light and moisture. Eye Drops: Store protected from light.

Probenecid decreases elimination. Antacids may reduce ofloxacin absorption, avoid for 2 hr either side of administration. Cimetidine may increase ofloxacin concentrations. Monitor blood glucose in patients on antidiabetic medication. Potentially Fatal: Corticosteroids may increase risk of tendon rupture. Increases effects of oral anticoagulants, ciclosporin, theophylline. Increased risk of seizures with NSAIDs. Avoid in patients taking QT prolonging medication (e.g. class Ia or III antiarrythmics, astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines and some TCA).

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : TOFLOX 400MG TABLET

Generic name : Ofloxacin

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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brand name : TOFLOX 400MG TABLET

Generic name : Ofloxacin

Basic Info

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