TOPQUIN 200MG TABLET
Ofloxacin 200 mg
Indchemie Health Specialities
It is available as a tablet taken orally, with or without food. It also available as eye drops to instill into the affected eyes as directed by your physician.
Tablets: Store protected from light and moisture. Eye Drops: Store protected from light.
Hypersensitivity.
Tuberculosis : Definition: It is a chronic granulomatous infection caused by the bacterium mycobacterium tuberculae Pathogenesis: It is a chronic granulomatous infection caused mainly by the inhalation of tubercular bacilli. The bacilli enters the lungs and get deposited on the upper lobe of the lungs there it forms a primary complex. Once this complex is formed the disease spread through the lymphatic vessel to the adjacent organs or locally. Drugs: First line drugs: Isoniazid, Rifampicin, ethambutol and Pyrizanamide Second line drugs: Aminoglycosides like Amikacin, kanamycin. Polypeptides like capreomycin. Fluoroquinolones like ciprofloxacin, levofloxacin, moxifloxacin Thioamides like ethionamide, prothionamide Cycloserine Para aminosalicylic acid Third line drugs : Rifabutin Macrolides like clarythromycin Linezolid Thioacetazone Vitamin D Thioridazine
Probenecid decreases elimination. Antacids may reduce ofloxacin absorption, avoid for 2 hr either side of administration. Cimetidine may increase ofloxacin concentrations. Monitor blood glucose in patients on antidiabetic medication. Potentially Fatal: Corticosteroids may increase risk of tendon rupture. Increases effects of oral anticoagulants, ciclosporin, theophylline. Increased risk of seizures with NSAIDs. Avoid in patients taking QT prolonging medication (e.g. class Ia or III antiarrythmics, astemizole, terfenadine, cisapride, erythromycin, pentamidine, phenothiazines and some TCA).
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.