brand name : VHOPE 200MG TABLET

Generic name : Voriconazole

Basic Info

Use of Drug

Voriconazole is an azole antifungal used to treat a variety of fungal infections.

Category Of Drug

Antifungal

Side Effects

Most Common - Visual disturbances, fever, nausea, rash, vomiting, chills, headache, abnormal liver function, fast heart rate and hallucinations. 

Body as a Whole - Abdominal pain, flu-like syndrome and weakness. 

Heart - Chest pain, vein inflammation, low blood pressure and facial swelling. 

Gastrointestinal - Nausea, vomiting, diarrhea, loss of appetite, difficulty in swallowing, indigestion, dry mouth, reflex and flatulence. 

Liver - Jaundice and liver inflammation. 

Blood - Blood dyscrasias, bruising and swelling in the extremities. 

Central Nervous System - Dizziness, hallucinations, confusion, depression, anxiety, tremor, agitation and tingling. 

Respiratory - Respiratory distress syndrome, sinus inflammation, nose bleed and difficulty in breathing. 

Skin - Rash, itching, sensitivity to light, hair loss and skin inflammation. 

Genitourinary - Kidney failure, blood in urine, impotence, urinary incontinence, urinary retention, urinary tract infection and vaginal bleeding.

Drug Dose Information

Usual Adult Dose for Aspergillosis -- Invasive:
Loading dose: 6 mg/kg IV every 12 hours for 2 doses

Maintenance dose:
IV:
Invasive aspergillosis and serious fungal infections due to Fusarium species and Scedosporium apiospermum: 4 mg/kg IV every 12 hours

Treatment must be started with the IV loading dose on Day 1 followed by the maintenance dose. IV therapy should continue for at least 7 days. Once the patient has clinically improved and can tolerate medication given by mouth, the oral tablet form or oral suspension form of voriconazole may be utilized.

Candidemia in nonneutropenic patients and other deep tissue Candida infections: 3 to 4 mg/kg IV every 12 hours

During clinical trials, patients with candidemia received 3 mg/kg IV every 12 hours as primary therapy, while patients with other deep tissue Candida infections received 4 mg/kg as salvage therapy. Appropriate dose should be based on the nature and severity of the infection.

Oral:
Less than 40 kg: 100 mg oral

Precautions

History of heart problems
Abnormal electrocardiogram (ECG)
Low level of blood minerals
Liver, kidney, pancreas, or blood disease
Who have taken chemotherapy treatment
Any allergy
Who are taking other medications
Pregnancy 
Breastfeeding

Brand Information

Brand Name	VHOPE 200MG TABLET
Contains	Voriconazole200 mg
Manufacturer Name	Torrent Pharmaceuticals Ltd

Brand Specifications
	Unit	Quantity	Price	Type
1	4's	1 strip	3333.3200	Tablet

How To Take

It is available as a tablet taken orally 1 hour before food.

Storage

Store it at controlled room temperature (15° - 30°C)

GERD : Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus The treatments for GERD include lifestyle modifications, medications, and possibly surgery. Initial treatment is frequently with a proton-pump inhibitor such as omeprazole.

Peptic ulcer disease : A peptic ulcer is a defect in the lining of the stomach or the first part of the small intestine, an area called the duodenum.A peptic ulcer in the stomach is called a gastric ulcer. An ulcer in the duodenum is called a duodenal ulcer. Major causes of Peptic ulcer disease(PUD) are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs), especially in patients with risk factors such as smoking and alcohol use. Diagnostic testing for PUD includes procedures used to document the presence of an ulcer, usually endoscopy, and tests that document the presence of H. pylori infection. Eradication of H. pylori, involving the use of at least two antibiotics and a proton-pump inhibitor (PPI) for 10 to 14 days, plays a major role in curing PUD. Antibiotics to treat PUD include clarithromycin , amoxicillin, tetracycline, or metronidazole. Proton pump inhibitors (omeprazole, lansoprazole or esomeprazole), bismuth subsalicylate and ulcer protectants( sucralfate) are the other mainstays in PUD treatment.

Zollinger–Ellison syndrome : Zollinger-Ellison syndrome is a rare disorder that occurs when one or more tumors form in the pancreas and duodenum. The tumors, called gastrinomas, release large amounts of gastrin that cause the stomach to produce large amounts of acid. Normally, the body releases small amounts of gastrin after eating, which triggers the stomach to make gastric acid that helps break down food and liquid in the stomach. The extra acid causes peptic ulcers to form in the duodenum and elsewhere in the upper intestine. The tumors seen with Zollinger-Ellison syndrome are sometimes cancerous and may spread to other areas of the body. MEDICATION : A class of medications called proton pump inhibitors (PPIs) includes: esomeprazole (Nexium) lansoprazole (Prevacid) pantoprazole (Protonix) omeprazole (Prilosec or Zegerid) dexlansoprazole (Dexilant)

Interactions

Voriconazole may interact with omeprazole, clopidogrel, cyclosporine, phenytoin, OCPs, tacrolimus, anti-HIV/AIDS drugs, prednisolone, warfarin, alfentanil, methadone, NSAIDs, tranquilizers, anti-hypertensive drugs, statins, vincristine, vinblastine, calcium-channel blockers and oral anti-diabetic drugs.

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drug’s Side effects

It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.

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brand name : VHOPE 200MG TABLET

Generic name : Voriconazole

Basic Info

Use of Drug

Category Of Drug

Side Effects

Drug Dose Information

Precautions

Brand Information

How To Take

Storage

Contra Indications

Diseases

Interactions

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drug’s Side effects

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brand name : VHOPE 200MG TABLET

Generic name : Voriconazole

Basic Info

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drug’s Side effects

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