Xigris
DROTRECOGIN ALFA
Eli Lilly And Company (India) Pvt.Ltd.
It is available as a solution to be injected by a doctor or hospital staff.
Store it in refrigerator at 2-8°C, and in an airtight container. Do not freeze it.
Internal bleeding Intracranial neoplasm or cerebral herniation Thrombocytopenia Not recommended for use in children under 18 years or in single organ failure.
Sepsis : Sepsis is a potentially life-threatening complication of an infection. Sepsis occurs when chemicals released into the bloodstream to fight the infection trigger inflammation throughout the body. This inflammation can trigger a cascade of changes that can damage multiple organ systems, causing them to fail. SYMPTOMS In general, symptoms of sepsis can include: • Chills • Confusion or delirium • Fever or low body temperature (hypothermia) • Light-headedness due to low blood pressure • Rapid heartbeat • Shaking • Skin rash • Warm skin TREATMENT Antibiotics are usually given through a vein (intravenously). Oxygen and large amounts of fluids are given through a vein. Other medical treatments include: • Medications that increase blood pressure • Dialysis if there is kidney failure • A breathing machine (mechanical ventilation) if there is lung failure
May increase the anticoagulant effect of other anticoagulants. Concurrent use with ibritumomab or prostacyclin analogues may increase risk of bleeding. NSAIDs and pentosan polysulfate sodium may increase the anticoagulant effect of anticoagulants. Salicylates may increase the adverse effect of drotrecogin alfa. May increase the adverse effect of tositumomab and iodine I 131 tositumomab.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.