CALPOL T TABLET
Paracetamol 325 mg ,Tramadol 37.5 mg
Glaxo Smithkline Pharmaceuticals Lt
Taken orally. Tablets must be swallowed whole, with a sufficient quantity of liquid. They must not be broken or chewed.
Store between 15 - 30°C (59 - 86°F).
Not recommended in severe renal impairment (CrCl <10 ml/minutes). Severe respiratory insufficiency, liver disease or opioid dependent patients. Increased intracranial pressure or head injury, patients at risk of seizures or on drugs that may lower the seizure threshold (e.g. SSRI, TCA, antipsychotics, centrally acting analgesics or local anaesthesia), biliary tract disorders, in a state of shock or unconsciousness.
Anemia : Anemia is the most common disorder of the blood. Anemia is a medical condition in which a decrease in number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. Anemic men hemoglobin level is less than 13.5 gram/100 and for a anemic women hemoglobin level is less than 12.0 gram/100 ml. Anemia is caused by either a decrease in production of red blood cells or hemoglobin, or an increase in loss or destruction of red blood cells. Some patients with anemia have no symptoms. Others may feel tired, easily fatigued, appear pale, a feeling of heart racing, short of breath, and/or worsening of heart problems. Anemia can be detected by a simple blood test called a complete blood cell count (CBC). The treatment of the anemia varies greatly and very much depends on the particular cause. Treatment – Treatment of anemia is done by 1. Oral iron 2. Injectable iron 3. Blood transfusions 4. Human Erythropoietin Injection
Increased risk serotonin syndrome with SSRI and triptans. Increased risk of seizures of SSRI, TCA, antipsychotics, centrally acting analgesics or local anaesthesia. Decreased tramadol levels with carbamazepine. Decreased analgesic efficacy of tramadol with ondansetron. Increased INR with warfarin. Potentially Fatal: Increased risk of serotonin syndrome with MAOIs, avoid concurrent use or within 2 weeks of discontinuation from MAOIs. Increased risk of CNS and respiratory depression with CNS depressants (e.g. alcohol, opioids, anaesthetic agents, narcotics, phenothiazines, tranquilizers or sedative hypnotics).
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.