DINAX T 500MG/50MG TABLET
Paracetamol500 mg+Tramadol50 mg
Colinz Laboratories Ltd
Taken orally. Tablets must be swallowed whole, with a sufficient quantity of liquid. They must not be broken or chewed.
Store between 15 - 30°C (59 - 86°F).
Not recommended in severe renal impairment (CrCl <10 ml/minutes). Severe respiratory insufficiency, liver disease or opioid dependent patients. Increased intracranial pressure or head injury, patients at risk of seizures or on drugs that may lower the seizure threshold (e.g. SSRI, TCA, antipsychotics, centrally acting analgesics or local anaesthesia), biliary tract disorders, in a state of shock or unconsciousness.
Amenorrhea : Is the absence of a menstrual period in a woman of reproductive age, which may temporary or permanent. Amenorrhea can be classified as primary or secondary. Primary Amenorrhea It is defined as an absence of secondary sexual characteristics by age 14 with no menarche or normal secondary sexual characteristics but no menarche by 16 years of age. And it may due to congenital absence of the uterus, failure of the ovary to receive or maintain egg cells or delay in pubertal development. Where as secondary Amenorrhea is the absence of menstrual periods for three consecutive cycles or a time period of more than six months in a woman who was previously menstruating and is often caused by hormonal disturbances from the hypothalamus and the pituitary gland, from premature menopause or intrauterine scar formation. Treatment 1. Drugs for treatment of Primary Amenorrhea are Estrogen and Progesterone 2. Drugs for treatment of Secondary Amenorrhea are Medroxyprogesterone, Progesterone and Norethindrone acetate
Increased risk serotonin syndrome with SSRI and triptans. Increased risk of seizures of SSRI, TCA, antipsychotics, centrally acting analgesics or local anaesthesia. Decreased tramadol levels with carbamazepine. Decreased analgesic efficacy of tramadol with ondansetron. Increased INR with warfarin. Potentially Fatal: Increased risk of serotonin syndrome with MAOIs, avoid concurrent use or within 2 weeks of discontinuation from MAOIs. Increased risk of CNS and respiratory depression with CNS depressants (e.g. alcohol, opioids, anaesthetic agents, narcotics, phenothiazines, tranquilizers or sedative hypnotics).
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.