GLIMITAB M 2MG/500MG TABLET
Glimepiride2 mg,Metformin500 mg
Centaur pharmaceuticals pvt ltd.
It is available as a tablet taken orally, with food
Store protected from moisture at temperature not exceeding 30°C.
Hypersensitivity Pregnancy Diabetic ketoacidosis
Hypertension : .Edema : Edema is swelling caused by excess fluid trapped in your body's tissues. Although edema can affect any part of your body, it's most commonly noticed in your hands, arms, feet, ankles and legs. Edema can be the result of medication, pregnancy or an underlying disease — often heart failure, kidney disease or cirrhosis of the liver. Taking medication to remove excess fluid and reducing the amount of salt in your food usually relieves edema. When edema is a sign of an underlying disease, the disease itself requires separate treatment. There are many types of edema. The most common ones are: ? Peripheral edema - in the feet (pedal edema), ankles, legs, hands and arms. ? Cerebral edema - in and around the brain (cerebral edema). ? Eye edema - in and around the eyes, e.g. macular edema, corneal edema, periorbital edema (puffiness around the eys. Macular edema is a serious complication of diabetic retinopathy. ? Signs and symptoms of edema include: • Swelling or puffiness of the tissue directly under your skin • Stretched or shiny skin • Skin that retains a dimple after being pressed for several seconds • Increased abdominal size Medications : • NSAIDs (ibuprofen, naproxen) • Calcium channel blockers • Corticosteroids (prednisone, methylprednisolone) • Pioglitazone and rosiglitazone • Pramiprexole
NSAIDs, salicylates, sulphonamides, chloramphenicol, coumarin, probenecid, CYP2C9 inhibitors, fibric acid derivatives, pegvisomant, TCAs, MAOIs and ß-adrenergic blockers may potentiate the hypoglycaemic action of glimepiride. Thiazides and other diuretics, corticosteroids, phenothiazines, thyroid products, oestrogens, oral contraceptives, phenytoin, nicotinic acid, sympathomimetics, rifampicin, CYP2C9 inducers and isoniazid may reduce hypoglycaemic effect of glimepiride. May increase the serum levels of ciclosporin. Serum levels may be increased by fluconazole.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.