Isordil
ISOSORBIDE DINITRATE
Wyeth Pharmaceuticals
It is available as a tablet taken orally, with or without food.
Store at a temperature not exceeding 30°C.
Hypersensitivity to nitrates Hypotension Hypovolaemia Myocardial infarction Hypertrophic obstructive cardiomyopathy Aortic stenosis Cardiac tamponade Constrictive pericarditis Mitral stenosis Marked anaemia Head trauma Cerebral haemorrhage Angle-closure glaucoma
Angina : Definition: Angina is chest pain or discomfort that occurs when an area of the heart is deprived of oxygen. It is typically described as a crushing or squeezing sensation in the chest and may radiate to the jaw, shoulders, arm or back. It is usually a symptom of underlying heart disease, such as coronary artery disease. Angina can be classified into two i.e Stable Angina and Unstable Angina Stable Angina - Usually results from atherosclerotic plaques in the coronary arteries. Acute attacks of stable angina should be managed with (1) Nitrates - Glyceryl trinitrate, Isosorbide dinitrate (2) Antiplatelet drugs - Aspirin (3) Calcium-channel blockers - Verapamil , Diltiazem,Nifedipine, nicardipine, amlodipine, and felodipine (4) Other antianginal drugs - Nicorandil and Ivabradine Unstable Angina - usually due to plaque rupture and may occur either in patients with a history of stable angina or in those with previously silent coronary artery disease. Unstable angina (UA) (also "c
Increased hypotensive effects with alcohol or vasodilators. Marked orthostatic hypotension may occur when used with calcium channel blockers. Vasodilatory effect may be reduced with dihydroergotamine. Ergotamine effects may be enhanced. Reduced effectiveness of sublingual form with disopyramide.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.