DUXET M 20MCG/1500MCG CAPSULE
Duloxetine 20 mcg ,Methylcobalamin 1500 mcg
Unichem Laboratories Ltd
Itis available as a capsule taken orally. It is usually taken once or twice a day with or without food.
Store at 25°C. Store it in air tight container and keep away from children.
Hypersensitivity Uncontrolled narrow-angle glaucoma. Concomitant use or within 2 wk of MAOIs Renal and hepatic impairment.
Depression : Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings and sense of well-being In general the type of treatment includepsychotherapy and/or antidepressants, alternative therapies, or active intervention. The most important classes of antidepressants are the selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Other drugs used or proposed for the treatment of depression include buprenorphine,tryptophan,low-dose antipsychotics,and St John's wort.
Increased risk of hepatic toxicity in patients with substantial alcohol use. Increased risk of serotonin syndrome when used with 5HT1 receptor agonists, MAOIs, lithium, tramadol or St John's wort. Avoid concurrent use with drugs that inhibit hepatic enzymes CYP1A2 and CYP2D6. Anticoagulants: May increase bleeding risk. Drugsthat reduce gastric acidity: May cause premature breakdown of duloxetin's protective coating and erly release of the drugs.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.