NEUROXETIN 20MG/0.5MG CAPSULE
Duloxetine 20 mg ,Methylcobalamin 0.5 mg
Aristo
Itis available as a capsule taken orally. It is usually taken once or twice a day with or without food.
Store at 25°C. Store it in air tight container and keep away from children.
Hypersensitivity Uncontrolled narrow-angle glaucoma. Concomitant use or within 2 wk of MAOIs Renal and hepatic impairment.
Depression : Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behavior, feelings and sense of well-being In general the type of treatment includepsychotherapy and/or antidepressants, alternative therapies, or active intervention. The most important classes of antidepressants are the selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). Other drugs used or proposed for the treatment of depression include buprenorphine,tryptophan,low-dose antipsychotics,and St John's wort. Panic attack : Panic attacks are periods of intense fear or apprehension that are of sudden onset and of variable duration from minutes to hours.Panic attacks usually begin abruptly, may reach a peak within 10 to 20 minutes, but may continue for hours in some cases.Panic attacks usually subside on their own over the next several hours.Drug therapy include Benzodiazepines (alprazolam, clonazepam and lorazepam), Beta Blockers( carvedilol, propranolol, and timolol), Selective Serotonin Reuptake Inhibitors (fluoxetine, paroxetine and sertraline) and Selective and Norepinephrine Reuptake Inhibitors (Venlafaxine ). Social Anxiety Disorder (social phobia) : Social anxiety disorder, also called social phobia, is an anxiety disorder in which a person has an excessive and unreasonable fear of social situations. Anxiety (intense nervousness) and self-consciousness arise from a fear of being closely watched, judged, and criticized by others. A person with social anxiety disorder is afraid that he or she will make mistakes, look bad, and be embarrassed or humiliated in front of others. The fear may be made worse by a lack of social skills or experience in social situations. The anxiety can build into a panic attack. As a result of the fear, the person endures certain social situations in extreme distress or may avoid them altogether. In addition, people with social anxiety disorder often suffer "anticipatory" anxiety -- the fear of a situation before it even happens -- for days or weeks before the event. In many cases, the person is aware that the fear is unreasonable, yet is unable to overcome it. People with social anxiety disorder suffer from distorted thinking, including false beliefs about social situations and the negative opinions of others. Without treatment, social anxiety disorder can negatively interfere with the person's normal daily routine, including school, work, social activities, and relationships. People with social anxiety disorder may be afraid of a specific situation, such as speaking in public. However, most people with social anxiety disorder fear more than one social situation. Other situations that commonly provoke anxiety include: • Eating or drinking in front of others. • Writing or working in front of others. • Being the center of attention. • Interacting with people, including dating or going to parties. • Asking questions or giving reports in groups. • Using public toilets. • Talking on the telephone. Medication Selective serotonin reuptake inhibitors (SSRIs), a class of antidepressants, are first choice medication for generalized social phobia but a second line treatment. Compared to older forms of medication, there is less risk of tolerability and drug dependency associated with SSRIs. Benzodiazepines such as clonazepam are an alternative to SSRIs. The novel antidepressant mirtazapine has been studied for the treatment of social anxiety disorder, and rendered mixed results. Another atypical antidepressant,bupropion, has shown success in an open trial.
Increased risk of hepatic toxicity in patients with substantial alcohol use. Increased risk of serotonin syndrome when used with 5HT1 receptor agonists, MAOIs, lithium, tramadol or St John's wort. Avoid concurrent use with drugs that inhibit hepatic enzymes CYP1A2 and CYP2D6. Anticoagulants: May increase bleeding risk. Drugsthat reduce gastric acidity: May cause premature breakdown of duloxetin's protective coating and erly release of the drugs.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.