SYLONEX 40MG TABLET
Duloxetine 40 mg
Psycoremedies Ltd
Itis available as a capsule taken orally. It is usually taken once or twice a day with or without food.
Store at 25°C. Store it in air tight container and keep away from children.
Hypersensitivity Uncontrolled narrow-angle glaucoma. Concomitant use or within 2 wk of MAOIs Renal and hepatic impairment.
Allergic rhinitis : Allergic rhinitis is an allergic inflammation of the nasal airways. It occurs when an allergen, such as pollen, dust, or animal dander (particles of shed skin and hair) is inhaled by an individual with a sensitized immune system. In such individuals, the allergen triggers the production of the antibody immunoglobulin E (IgE), which binds to mast cells and basophils containing histamine.Allergic rhinitis caused by pollens commonly called hay fever or seasonal allergy. Drugs Used (1) ANTIHISTAMINES - Azelastine Hydrochloride (2) CORTICOSTEROIDS - Beclometasone, Betamethasone,Budesonide,Fflunisolide,Fluticasone, Mometasone, and Triamcinolone (3) DECONGESTANTS - Cromoglicate Hay fever : Allergic rhinitis caused by grass pollens, it is known as hay fever. Treatment Antihistamines Antihistamine drugs can be taken orally and nasally to control symptoms such as sneezing, rhinorrhea, itching, and conjunctivitis. Steroids Intranasal corticosteroids are used to control symptoms associated with sneezing, rhinorrhea, itching, and nasal congestion. Other Other measures that may be used second line include: decongestants, cromolyn, leukotriene receptor antagonists, and nonpharmacologic therapies such as nasal irrigation Urticaria : Urticaria commonly referred to as hives, is a kind of skin rash notable for pale red, raised, itchy bumps. Hives might also cause a burning or stinging sensation. Hives are frequently caused byallergic reactions; however, there are many nonallergic causes. Most cases of hives lasting less than six weeks (acute urticaria) are the result of an allergic trigger. Chronic urticaria (hives lasting longer than six weeks) is rarely due to an allergy. Wheals (raised areas surrounded by a red base) from urticaria can appear anywhere on the surface of the skin. Whether the trigger is allergic or not, a complex release of inflammatory mediators, including histamine from cutaneous mast cells, results in fluid leakage from superficial blood vessels. Wheals may be pinpoint in size, or several inches in diameter. Angioedema is a related condition (also from allergic and nonallergic causes), though fluid leakage is from much deeper blood vessels in the subcutaneous or submucosal layers. Individual hives that are painful, last more than 24 hours, or leave a bruise as they heal are more likely to be a more serious condition calledurticarial vasculitis. Hives caused by stroking the skin (often linear in appearance) are due to a benign condition called dermatographic urticaria. Treatment Antihistamine diphenhydramine, Tricyclic antidepressants, hydrocortisone, fluocinonide, prednisone,
Increased risk of hepatic toxicity in patients with substantial alcohol use. Increased risk of serotonin syndrome when used with 5HT1 receptor agonists, MAOIs, lithium, tramadol or St John's wort. Avoid concurrent use with drugs that inhibit hepatic enzymes CYP1A2 and CYP2D6. Anticoagulants: May increase bleeding risk. Drugsthat reduce gastric acidity: May cause premature breakdown of duloxetin's protective coating and erly release of the drugs.
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It is any effect of a drug, chemical, or other medicine that is in addition to its intended effect, especially an effect that is harmful or unpleasant.